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一名3个月大患有巩膜角膜病患儿穿透性角膜移植术的结果。

Outcome of a penetrating keratoplasty in a 3-month-old child with sclerocornea.

作者信息

Pohlmann Dominika, Rossel Mirjam, Salchow Daniel J, Bertelmann Eckart

机构信息

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

出版信息

GMS Ophthalmol Cases. 2020 Aug 7;10:Doc35. doi: 10.3205/oc000162. eCollection 2020.

Abstract

Sclerocornea is a rare congenital anomaly with clouding of the peripheral cornea that possibly extends up to the center of the cornea. Characteristically, a clear distinction (limbus) between sclera and cornea is lacking. Early surgical treatment is essential for preventing amblyopia, but penetrating keratoplasty in children carries a relatively high risk of complications. Especially for sclerocornea, penetrating keratoplasty has generally been reported to have a poor surgical outcome and a high risk of complications, including corneoscleral adhesions. Here, we report the 4-year follow-up on a child with sclerocornea, who was successfully operated on at the age of 3 months and had a favorable outcome. Our findings suggest that in some cases, penetrating keratoplasty may be an option to treat sclerocornea in young children.

摘要

硬化性角膜是一种罕见的先天性异常,其周边角膜混浊,可能延伸至角膜中央。其特征是巩膜与角膜之间缺乏清晰的界限(角膜缘)。早期手术治疗对于预防弱视至关重要,但儿童穿透性角膜移植术的并发症风险相对较高。特别是对于硬化性角膜,一般报道称穿透性角膜移植术的手术效果较差且并发症风险高,包括角膜巩膜粘连。在此,我们报告一名硬化性角膜患儿的4年随访情况,该患儿在3个月大时成功接受手术,预后良好。我们的研究结果表明,在某些情况下,穿透性角膜移植术可能是治疗幼儿硬化性角膜的一种选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cfb7/7452949/276ba9fad21d/OC-10-35-g-001.jpg

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