Pohlmann Dominika, Rossel Mirjam, Salchow Daniel J, Bertelmann Eckart
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
GMS Ophthalmol Cases. 2020 Aug 7;10:Doc35. doi: 10.3205/oc000162. eCollection 2020.
Sclerocornea is a rare congenital anomaly with clouding of the peripheral cornea that possibly extends up to the center of the cornea. Characteristically, a clear distinction (limbus) between sclera and cornea is lacking. Early surgical treatment is essential for preventing amblyopia, but penetrating keratoplasty in children carries a relatively high risk of complications. Especially for sclerocornea, penetrating keratoplasty has generally been reported to have a poor surgical outcome and a high risk of complications, including corneoscleral adhesions. Here, we report the 4-year follow-up on a child with sclerocornea, who was successfully operated on at the age of 3 months and had a favorable outcome. Our findings suggest that in some cases, penetrating keratoplasty may be an option to treat sclerocornea in young children.
硬化性角膜是一种罕见的先天性异常，其周边角膜混浊，可能延伸至角膜中央。其特征是巩膜与角膜之间缺乏清晰的界限（角膜缘）。早期手术治疗对于预防弱视至关重要，但儿童穿透性角膜移植术的并发症风险相对较高。特别是对于硬化性角膜，一般报道称穿透性角膜移植术的手术效果较差且并发症风险高，包括角膜巩膜粘连。在此，我们报告一名硬化性角膜患儿的4年随访情况，该患儿在3个月大时成功接受手术，预后良好。我们的研究结果表明，在某些情况下，穿透性角膜移植术可能是治疗幼儿硬化性角膜的一种选择。
