Dana M R, Schaumberg D A, Moyes A L, Gomes J A, Laibson P R, Holland E J, Sugar A, Sugar J
Cornea Service, Wills Eye Hospital, Philadelphia, PA 19107, USA.
Arch Ophthalmol. 1995 Dec;113(12):1503-7. doi: 10.1001/archopht.1995.01100120033003.
To characterize the outcome of penetrating keratoplasty in children for the visual rehabilitation of corneal injury.
Multicenter retrospective study of the outcome of penetrating keratoplasty for ocular trauma in children.
All children aged 12 years and younger who underwent penetrating keratoplasty between January 1975 and May 1993 for penetrating corneal (n = 18) or corneoscleral (n = 3) trauma and nonpenetrating corneal trauma (n = 1).
Graft survival and postoperative visual acuity improvement.
Twenty-two children underwent 25 penetrating keratoplasties during the study period. Graft survival was 84% at 1 year and 70% at 2 years after surgery. Visual acuity improved in 15 (83%) of the 18 children with measurable preoperative and postoperative vision. Children with posterior segment injury before keratoplasty were less likely to maintain a clear graft (P = .04) and less likely to have improved vision postoperatively (P = .06). Children who received amblyopia treatment and appropriate optical correction postoperatively were more likely to have visual improvement than those who did not (P = .02).
Penetrating keratoplasty for corneal trauma is generally a successful operation in the pediatric age group, with visual improvement seen in more than four fifths of cases. Graft survival and visual outcome are best in patients with trauma limited to the anterior segment. Aggressive postoperative refractive correction and amblyopia management also appear to contribute to a better visual outcome in pediatric keratoplasty.
描述儿童穿透性角膜移植术在角膜损伤视觉康复方面的效果。
关于儿童眼外伤穿透性角膜移植术效果的多中心回顾性研究。
1975年1月至1993年5月间,所有12岁及以下因穿透性角膜(n = 18)或角巩膜(n = 3)外伤以及非穿透性角膜外伤(n = 1)而接受穿透性角膜移植术的儿童。
植片存活情况及术后视力改善情况。
研究期间,22名儿童接受了25次穿透性角膜移植术。术后1年植片存活率为84%,2年时为70%。18名术前和术后视力可测量的儿童中,15名(83%)视力得到改善。角膜移植术前存在后段损伤的儿童,植片保持透明的可能性较小(P = 0.04),术后视力改善的可能性也较小(P = 0.06)。术后接受弱视治疗并进行适当光学矫正的儿童比未接受者视力改善的可能性更大(P = 0.02)。
对于儿童年龄组,角膜外伤的穿透性角膜移植术总体上是一种成功的手术,超过五分之四的病例视力得到改善。前节损伤局限的患者植片存活和视觉效果最佳。积极的术后屈光矫正和弱视治疗似乎也有助于改善儿童角膜移植术的视觉效果。