• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

颌面部缺损的微血管重建:121例连续病例的结局与并发症回顾性分析

Microvascular reconstruction for maxillofacial defects: a retrospective analysis of outcomes and complications in 121 consecutive cases.

作者信息

Kim SeongRyoung, Lee Dong-Hun, Ahn Kang-Min

机构信息

Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan, Asan Medical Center, 88 Olympic-ro, 43-gil, Songpa-gu, Seoul, 05505 Korea.

出版信息

Maxillofac Plast Reconstr Surg. 2020 Aug 26;42(1):29. doi: 10.1186/s40902-020-00273-4. eCollection 2020 Dec.

DOI:10.1186/s40902-020-00273-4
PMID:32884927
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7447709/
Abstract

BACKGROUND

Microvascular reconstruction is the treatment of choice after oral cancer ablation surgery. There are few published studies of free flap survival among Korean populations. This study aimed to determine the survival rate after 121 consecutive cases of maxillofacial microvascular reconstruction and to analyze the complications associated with microsurgery.

METHODS

This study included consecutive patients who underwent microsurgical reconstruction with free flaps, from January 2006 through September 2019, performed by a single surgeon at the oral and maxillofacial surgery department of a tertiary medical center. A total of 121 cases were reviewed retrospectively. The flap survival rate, flap type, radiotherapy history, complications, and treatment results were analyzed.

RESULTS

Four different flap types were used for microvascular reconstruction: radial forearm ( = 65), fibula ( = 34), latissimus dorsi ( = 21), and serratus anterior muscle with rib bone free flap ( = 1). Total necrosis of the flap was found in four cases (two latissimus dorsi flaps and two fibular flaps). The free flap survival rate was 97.5%. Nineteen patients received radiotherapy before surgery, and none of them experienced flap failure. The mean operation time was 334 ± 83.1 min, and the mean ischemic time was 48.9 ± 12.7 min.

CONCLUSIONS

The success rate was reliable and comparable with previous studies. The success rate was not affected by radiation therapy. Free flaps can be safely used even after radiation treatment.

摘要

背景

微血管重建是口腔癌切除术后的首选治疗方法。关于韩国人群中游离皮瓣存活情况的已发表研究较少。本研究旨在确定121例连续的颌面微血管重建术后的存活率,并分析与显微外科手术相关的并发症。

方法

本研究纳入了2006年1月至2019年9月在一家三级医疗中心口腔颌面外科由一名外科医生进行游离皮瓣显微外科重建的连续患者。共对121例病例进行回顾性分析。分析皮瓣存活率、皮瓣类型、放疗史、并发症及治疗结果。

结果

微血管重建使用了四种不同的皮瓣类型:桡侧前臂皮瓣(n = 65)、腓骨皮瓣(n = 34)、背阔肌皮瓣(n = 21)和带肋骨的前锯肌游离皮瓣(n = 1)。发现4例皮瓣完全坏死(2例背阔肌皮瓣和2例腓骨皮瓣)。游离皮瓣存活率为97.5%。19例患者术前接受了放疗,且均未出现皮瓣失败。平均手术时间为334 ± 83.1分钟,平均缺血时间为48.9 ± 12.7分钟。

结论

成功率可靠,与先前研究相当。成功率不受放疗影响。即使在放疗后也可安全使用游离皮瓣。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/7447709/e8a01efc9c45/40902_2020_273_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/7447709/ed211d9bcfc3/40902_2020_273_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/7447709/4850f64029ad/40902_2020_273_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/7447709/be4e1a320b32/40902_2020_273_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/7447709/e8a01efc9c45/40902_2020_273_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/7447709/ed211d9bcfc3/40902_2020_273_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/7447709/4850f64029ad/40902_2020_273_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/7447709/be4e1a320b32/40902_2020_273_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/7447709/e8a01efc9c45/40902_2020_273_Fig4_HTML.jpg

相似文献

1
Microvascular reconstruction for maxillofacial defects: a retrospective analysis of outcomes and complications in 121 consecutive cases.颌面部缺损的微血管重建:121例连续病例的结局与并发症回顾性分析
Maxillofac Plast Reconstr Surg. 2020 Aug 26;42(1):29. doi: 10.1186/s40902-020-00273-4. eCollection 2020 Dec.
2
Microsurgical reconstruction for radiation necrosis: an evolving disease.放射性坏死的显微外科重建:一种不断演变的疾病。
J Reconstr Microsurg. 2007 May;23(4):225-30. doi: 10.1055/s-2007-981505.
3
Microsurgical reconstruction of the head and neck: interdisciplinary collaboration between head and neck surgeons and plastic surgeons in 305 cases.头颈部的显微外科重建:头颈外科医生与整形外科医生的跨学科合作——305例病例分析
Ann Plast Surg. 1996 Jan;36(1):37-43. doi: 10.1097/00000637-199601000-00008.
4
A Standard Algorithm for Reconstruction of Scalp Defects With Simultaneous Free Flaps in an Interdisciplinary Two-Team Approach.一种跨学科双团队方法中同时使用游离皮瓣修复头皮缺损的标准算法。
Front Oncol. 2019 Oct 25;9:1130. doi: 10.3389/fonc.2019.01130. eCollection 2019.
5
The Use of Venous Coupler Device in Free Tissue Transfers for Oral and Maxillofacial Reconstruction.静脉吻合器在口腔颌面重建游离组织移植中的应用
J Oral Maxillofac Surg. 2015 Nov;73(11):2225-31. doi: 10.1016/j.joms.2015.06.153. Epub 2015 Jun 20.
6
[15 years experience with microvascular free tissue transfert for repair of head and neck cancer defects].[微血管游离组织移植修复头颈癌缺损的15年经验]
Ann Otolaryngol Chir Cervicofac. 2002 Feb;119(1):31-8.
7
The combined latissimus dorsi-scapular free flap in head and neck reconstruction.背阔肌-肩胛游离联合皮瓣在头颈部重建中的应用
Arch Otolaryngol Head Neck Surg. 1991 Nov;117(11):1242-50. doi: 10.1001/archotol.1991.01870230058008.
8
Microvascular free flaps in head and neck cancer surgery in Finland 1986-1995.1986 - 1995年芬兰头颈癌手术中的微血管游离皮瓣
Acta Otolaryngol Suppl. 1997;529:245-6. doi: 10.3109/00016489709124134.
9
Outcomes of delayed abdominal-based autologous reconstruction versus latissimus dorsi flap plus implant reconstruction in previously irradiated patients.延迟腹部自体组织重建与背阔肌肌皮瓣加植入物重建用于既往接受过放疗患者的效果比较
Ann Plast Surg. 2012 Oct;69(4):380-2. doi: 10.1097/SAP.0b013e31824b3d6b.
10
Identification of Independent Risk Factors for Complications: A Retrospective Analysis of 163 Fibular Free Flaps for Mandibulofacial Reconstruction.并发症独立危险因素的识别:163例游离腓骨瓣用于下颌面部重建的回顾性分析
J Oral Maxillofac Surg. 2018 Jul;76(7):1571-1577. doi: 10.1016/j.joms.2017.12.026. Epub 2018 Jan 8.

引用本文的文献

1
Donor site outcomes and functional recovery are improved with superficial inferior epigastric artery perforator flap compared to radial forearm flap in oral and maxillofacial reconstruction.在口腔颌面重建中,与桡侧前臂皮瓣相比,腹壁下浅动脉穿支皮瓣供区预后及功能恢复更佳。
Am J Transl Res. 2025 May 15;17(5):3790-3801. doi: 10.62347/GYJH5711. eCollection 2025.
2
Progress of Ossification after Mandibular Reconstruction by Free Fibula Flap Depending on Different Timing of Radiotherapy: A Retrospective 3D Analysis by CT Scans.游离腓骨瓣下颌骨重建术后根据不同放疗时机的骨化进展:一项基于CT扫描的回顾性三维分析
J Clin Med. 2024 Jul 13;13(14):4104. doi: 10.3390/jcm13144104.
3

本文引用的文献

1
Head and Neck Reconstructive Surgery: Characterization of the One-Team and Two-Team Approaches.头颈重建手术:单团队与双团队方法的特征
J Oral Maxillofac Surg. 2020 Feb;78(2):295-304. doi: 10.1016/j.joms.2019.09.011. Epub 2019 Sep 18.
2
Geriatric Patients with Free Flap Reconstruction: A Comparative Clinical Analysis of 256 Cases.老年患者游离皮瓣重建术:256 例临床对比分析。
J Reconstr Microsurg. 2020 Feb;36(2):127-135. doi: 10.1055/s-0039-1697646. Epub 2019 Sep 23.
3
Factors Associated with Free Flap Failures in Head and Neck Reconstruction.
Reconstructive surgery and adjuvant radiotherapy for the multimodal approach in oral cancer: a single cancer centre experience.
口腔癌多模式治疗中的重建手术及辅助放疗:单癌症中心经验
Ann Med Surg (Lond). 2023 Oct 4;85(11):5314-5322. doi: 10.1097/MS9.0000000000001357. eCollection 2023 Nov.
4
Influence of Radiotherapy on Ossification of Vascularized Osseous Reconstruction of the Jaw: A Radiological Retrospective Cohort Study Based on Panoramic Radiographs.放疗对颌骨带血管骨重建骨化的影响:一项基于全景X线片的放射学回顾性队列研究
J Clin Med. 2022 Aug 27;11(17):5041. doi: 10.3390/jcm11175041.
5
Flap failure prediction in microvascular tissue reconstruction using machine learning algorithms.使用机器学习算法预测微血管组织重建中的皮瓣失败情况。
World J Clin Cases. 2022 Apr 26;10(12):3729-3738. doi: 10.12998/wjcc.v10.i12.3729.
6
The effect of FK506 (tacrolimus) loaded with collagen membrane and fibrin glue on promotion of nerve regeneration in a rat sciatic nerve traction injury model.负载胶原膜和纤维蛋白胶的FK506(他克莫司)对大鼠坐骨神经牵拉伤模型中神经再生促进作用的研究
Maxillofac Plast Reconstr Surg. 2022 Apr 6;44(1):14. doi: 10.1186/s40902-022-00339-5.
7
Functional and electron-microscopic changes after differential traction injury in the sciatic nerve of a rat.大鼠坐骨神经差异性牵拉伤后的功能及电子显微镜下的变化
Maxillofac Plast Reconstr Surg. 2021 May 1;43(1):12. doi: 10.1186/s40902-021-00297-4.
8
Titanium mesh and pedicled buccal fat pad for the reconstruction of maxillary defect: case report.钛网联合带蒂颊脂垫修复上颌骨缺损:病例报告
Maxillofac Plast Reconstr Surg. 2021 Mar 17;43(1):10. doi: 10.1186/s40902-021-00295-6.
与头颈部重建游离皮瓣失败相关的因素。
Otolaryngol Head Neck Surg. 2019 Oct;161(4):598-604. doi: 10.1177/0194599819860809. Epub 2019 Aug 6.
4
Free Flap Outcomes of Microvascular Reconstruction after Repeated Segmental Mandibulectomy in Head and Neck Cancer Patients.头颈部癌症患者多次节段性下颌骨切除术后的游离皮瓣转归。
Sci Rep. 2019 May 28;9(1):7951. doi: 10.1038/s41598-019-44467-x.
5
Association of Anesthesia Duration With Complications After Microvascular Reconstruction of the Head and Neck.麻醉持续时间与头颈部微血管重建术后并发症的关联。
JAMA Facial Plast Surg. 2018 May 1;20(3):188-195. doi: 10.1001/jamafacial.2017.1607.
6
Predictors of free flap loss in the head and neck region: A four-year retrospective study with 451 microvascular transplants at a single centre.头颈部游离皮瓣坏死的预测因素:一项在单一中心对451例微血管移植进行的为期四年的回顾性研究。
J Craniomaxillofac Surg. 2016 Sep;44(9):1292-8. doi: 10.1016/j.jcms.2016.04.029. Epub 2016 Apr 26.
7
Impact of microvascular free flap reconstruction in oral cavity cancer: our experience in 130 cases.微血管游离皮瓣重建术在口腔癌中的应用:我们130例病例的经验。
Acta Otorhinolaryngol Ital. 2015 Dec;35(6):386-93. doi: 10.14639/0392-100X-919.
8
Analysis of Microvascular Free Flap Failure Focusing on the Microscopic Findings of the Anastomosed Vessels.以吻合血管的显微镜检查结果为重点的游离微血管皮瓣失败分析。
J Craniofac Surg. 2015 Oct;26(7):2047-51. doi: 10.1097/SCS.0000000000002111.
9
Mandibular reconstruction using fibula free flap harvested using a customised cutting guide: how we do it.使用定制切割导板采集游离腓骨瓣进行下颌骨重建:我们的做法。
Acta Otorhinolaryngol Ital. 2015 Jun;35(3):198-201.
10
Recent advances in head and neck free tissue transfer.头颈部游离组织移植的最新进展。
Curr Opin Otolaryngol Head Neck Surg. 2015 Aug;23(4):297-301. doi: 10.1097/MOO.0000000000000169.