酷似球部起病的肌萎缩侧索硬化的舌根部鳞状细胞癌。
Squamous cell carcinoma of the base of the tongue mimicking bulbar-onset amyotrophic lateral sclerosis.
作者信息
Lin Hsin-Pin, Lieberman Leora, Patel Mitesh, Chuquilin Miguel
机构信息
Department of Neurology, College of Medicine, University of Florida, Gainesville, FL, USA.
Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
出版信息
Heliyon. 2020 Aug 24;6(8):e04769. doi: 10.1016/j.heliyon.2020.e04769. eCollection 2020 Aug.
One-third of patients with amyotrophic lateral sclerosis (ALS) present with bulbar symptoms, exhibiting progressive dysphagia and dysarthria. In comparison, squamous cell carcinoma (SCC) of the tongue can cause tongue paralysis secondary to hypoglossal nerve infiltration. In rare cases, SCC can mimic motor neuron disease. Here, we describe a patient with SCC of the base of the tongue related to human papillomavirus infection who was initially misdiagnosed with bulbar-onset ALS.
三分之一的肌萎缩侧索硬化症（ALS）患者以延髓症状起病，表现为进行性吞咽困难和构音障碍。相比之下，舌鳞状细胞癌（SCC）可因舌下神经浸润导致舌麻痹。在罕见情况下，SCC可模仿运动神经元病。在此，我们描述一名与人类乳头瘤病毒感染相关的舌根SCC患者，该患者最初被误诊为延髓起病的ALS。
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