Routzong Megan R, Rostaminia Ghazaleh, Bowen Shaniel T, Goldberg Roger P, Abramowitch Steven D
Translational Biomechanics Laboratory, Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, USA.
Female Pelvic Medicine and Reconstructive Surgery (FPMRS), Division of Urogynecology, University of Chicago Pritzker School of Medicine, Northshore University HealthSystem, Skokie, IL, USA.
Comput Methods Biomech Biomed Engin. 2021 Feb;24(2):122-130. doi: 10.1080/10255842.2020.1813281. Epub 2020 Sep 4.
Obstructed defecation (OD) is common and may be related to compromised pelvic floor integrity. Magnetic resonance (MR) defecography and statistical shape modeling were used to define pelvic floor shape variations, hypothesizing that State (rest vs peak evacuation) and Group (control vs case) would significantly influence shape. 16 women underwent MR defecography (9 cases vs 7 controls). Midsagittal, 2D pelvic floors were segmented and aligned by corresponding points. Principal component scores were compared using a Two-Way Mixed MANOVA. Three modes described differences between State (p < 0.001) and Group (p = 0.023). The pelvic floor shape differed significantly between women with and without OD and during evacuation.
排便障碍（OD）很常见，可能与盆底完整性受损有关。磁共振（MR）排粪造影和统计形状建模用于定义盆底形状变化，假设状态（静息与排便峰值）和组别（对照组与病例组）会显著影响形状。16名女性接受了MR排粪造影（9例病例与7例对照）。通过对应点对矢状面二维盆底进行分割和对齐。使用双向混合多变量方差分析比较主成分得分。三种模式描述了状态（p < 0.001）和组别（p = 0.023）之间的差异。有和没有OD的女性之间以及排便期间盆底形状存在显著差异。
