Andrew's Sports Medicine & Orthopedic Center, 3143 Pelham Parkway, Pelham, AL 35124, USA.
American Sports Medicine Institute, 833 Saint Vincent's Drive, Suite 205, Birmingham, AL 35205, USA.
Regen Med. 2020 Jul;15(7):1851-1859. doi: 10.2217/rme-2019-0113. Epub 2020 Sep 4.
Bone marrow aspiration (BMA) is among a group of autologous cell-based therapies currently being explored to treat osteoarthritis (OA). This retrospective case study observed ten patients (13 knees) with severe knee OA who failed extensive conservative treatment and were treated with BMA injection using a novel, pure bone marrow aspiration (pBMA) technique. No adverse events were reported. More than 50% reduction in the visual analog scale score for pain was observed at 2- and 12-weeks post-procedure, showing statistical significance. At 64 ± 26 weeks post-procedure, average knee pain remained significantly less than pre-procedure. Therefore, patients with severe knee OA may achieve significant relief after a BMA injection obtained using this pure bone marrow aspiration technique.
骨髓抽吸术（BMA）是目前正在探索的一组自体细胞治疗方法之一，用于治疗骨关节炎（OA）。本回顾性病例研究观察了 10 名（13 膝）患有严重膝骨关节炎的患者，这些患者经广泛的保守治疗失败后，采用一种新的、纯骨髓抽吸术（pBMA）技术进行 BMA 注射治疗。未报告不良事件。术后 2 周和 12 周时，疼痛视觉模拟评分（VAS）的降幅超过 50%，具有统计学意义。术后 64±26 周时，平均膝关节疼痛明显低于术前。因此，使用这种纯骨髓抽吸技术进行 BMA 注射后，严重膝骨关节炎患者可能会获得显著缓解。
