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葡萄牙人口致命性心血管疾病 10 年风险评估:来自葡萄牙首次健康体检调查(INSEF 2015)的结果。

Estimation of the 10-Year Risk of Fatal Cardiovascular Disease in the Portuguese Population: Results from the First Portuguese Health Examination Survey (INSEF 2015).

机构信息

Departamento de Epidemiologia. Instituto Nacional de Saúde Doutor Ricardo Jorge. Lisboa; Escola Nacional de Saúde Pública. Centro de Investigação em Saúde Pública. Universidade NOVA de Lisboa. Lisboa. Portugal.

Departamento de Epidemiologia. Instituto Nacional de Saúde Doutor Ricardo Jorge. Lisboa. Portugal.

出版信息

Acta Med Port. 2020 Nov 2;33(11):726-732. doi: 10.20344/amp.13009. Epub 2020 Sep 4.

Abstract

INTRODUCTION

Cardiovascular disease is the leading cause of morbidity and mortality in Portugal and globally. Cardiovascular risk algorithms, namely the SCORE (Systematic Coronary Risk Evaluation), are recommended in the context of cardiovascular disease prevention. Our aim is to estimate and characterize the cardiovascular risk of the Portuguese population aged between 40 and 65 years old, in 2015, using the SCORE algorithm.

MATERIAL AND METHODS

This study was performed on a subsample of the first Portuguese National Health Examination Survey - INSEF, including all participants between 40 and 65 years old with available data on sex, age, smoking status, total cholesterol and systolic blood pressure (n = 2945). The prevalence of the cardiovascular risk categories were stratified by sex, age group, marital status, educational level, occupational activity, urbanization of living area, region and income.

RESULTS

In 2015, about 5.1% and 11.9% of the Portuguese resident population aged between 40 and 65 years old were, respectively, at high and very high risk of having a fatal CV event in the following 10 years. The highest prevalence of very high cardiovascular risk was found in males, individuals aged 60-65 years old, married or living with someone, without any formal education or just with the 1st cycle of basic education and belonging to the less skilled category of the occupational activity (C category) in comparison with the othercorresponding groups.

DISCUSSION

A previous national study found a similar proportion of the population at high/very high cardiovascular risk (19.5% versus 17.1%). Our study is representative of the adult Portuguese population and adopted the European Health Examination Survey procedures, which are essential for future comparisons with other European countries. Some of the limitations of this study include the possible participation bias and the non-calibration of the SCORE algorithm for the Portuguese population.

CONCLUSION

In 2015, a considerable proportion of the Portuguese population aged between 40 and 65 years old had a high or very high risk of developing a fatal cardiovascular event in the next 10 years. Due to the possible overestimation of the cardiovascular risk already reported in other European countries, it will be important to carry out a follow-up study to validate the adequacy of using the SCORE algorithm in the Portuguese population.

摘要

简介

心血管疾病是葡萄牙乃至全球发病率和死亡率的主要原因。心血管风险算法,即 SCORE(系统性冠状动脉风险评估),在心血管疾病预防中被推荐使用。我们的目的是使用 SCORE 算法估计和描述 2015 年葡萄牙 40 至 65 岁人群的心血管风险。

材料与方法

本研究基于葡萄牙首次国家健康检查调查(INSEF)的一个子样本,包括所有年龄在 40 至 65 岁之间、有性别、年龄、吸烟状况、总胆固醇和收缩压数据的参与者(n=2945)。按性别、年龄组、婚姻状况、教育程度、职业活动、居住地区的城市化程度、地区和收入对心血管风险类别进行分层。

结果

2015 年,葡萄牙 40 至 65 岁居民中,分别有 5.1%和 11.9%的人在未来 10 年内发生致命心血管事件的风险较高和极高。在男性、60-65 岁的人群、已婚或与他人同居、没有任何正规教育或只有基础教育第一周期的人群以及职业活动中技能程度较低的人群(C 类)中,极高心血管风险的比例最高。

讨论

此前的一项全国性研究发现,有类似比例的人群处于高/极高心血管风险(19.5%与 17.1%)。我们的研究代表了葡萄牙成年人口,采用了欧洲健康检查调查程序,这对于未来与其他欧洲国家进行比较至关重要。本研究的一些局限性包括可能存在的参与偏倚和 SCORE 算法对葡萄牙人口的非校准。

结论

2015 年,相当一部分葡萄牙 40 至 65 岁人群在未来 10 年内发生致命心血管事件的风险较高或极高。由于其他欧洲国家已经报告了心血管风险的可能高估,因此,开展一项后续研究以验证 SCORE 算法在葡萄牙人群中的适用性是很重要的。

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