Feng Zicong, Yang Yang, He Fengpu, Pang Kunjing, Ma Kai, Zhang Sen, Qi Lei, Wang Guanxi, Mao Fengqun, Yuan Jianhui, Li Shoujun
Paediatric Cardiac Surgery Centre, Fuwai Hospital, National Centre for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Cardiovascular Surgery, The First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou, China.
Eur J Cardiothorac Surg. 2020 Dec 1;58(6):1261-1268. doi: 10.1093/ejcts/ezaa264.
Surgical outcomes of supracardiac total anomalous pulmonary venous connection (TAPVC) repair by the posterior technique (PT) remain unsatisfactory. This study aimed to compare the outcomes of the modified L-shaped incision technique with the PT for supracardiac TAPVC repair.
From January 2009 to December 2019, 121 consecutive patients with supracardiac TAPVC undergoing surgical repair in our institution were included (L-group, n = 53; PT group, n = 68). A propensity score-matched analysis was performed. Patients with single-ventricle physiology or atrial isomerism were excluded. All clinical data were retrospectively analysed.
In the unmatched cohort, the median follow-up duration was 33 months (interquartile range 26-65 months). There were 5 operative mortalities (4.1%) and 12 late mortalities (9.9%). Postoperative pulmonary venous obstruction (PVO) was documented in 21 patients. After matching (52 pairs), the overall survival rate in the L-group was 88.2% at both 3 and 5 years. For the propensity score-matched patients with preoperative PVO (n = 20), statistically significant differences (P = 0.002) were found by Kaplan-Meier curves with freedom from death and postoperative PVO at 1 and 3 years of 100% and 85.7% [standard deviation (SD): 13.2%] in the L-group and 90% (SD: 9.5%) and 22.9% (SD: 14.1%) in the PT group, respectively. Multivariable analysis revealed that the use of the PT was an independent risk factor for death and postoperative PVO (hazard ratio 4.12, 95% confidence interval 1.12-15.16; P = 0.03).
The modified L-shaped incision technique provided an acceptable outcome for supracardiac TAPVC repair. Compared with PT, the modified L-shaped incision technique was significantly associated with decreased death and postoperative PVO in patients with obstructed supracardiac TAPVC.
采用后入路技术(PT)修复心上型完全性肺静脉异位连接(TAPVC)的手术效果仍不尽人意。本研究旨在比较改良L形切口技术与PT修复心上型TAPVC的效果。
纳入2009年1月至2019年12月在本机构连续接受手术修复的121例心上型TAPVC患者(L组,n = 53;PT组,n = 68)。进行倾向评分匹配分析。排除单心室生理或心房异构患者。对所有临床数据进行回顾性分析。
在未匹配队列中,中位随访时间为33个月(四分位间距26 - 65个月)。有5例手术死亡(4.1%)和12例晚期死亡(9.9%)。21例患者记录到术后肺静脉梗阻(PVO)。匹配后(52对),L组3年和5年的总生存率均为88.2%。对于倾向评分匹配的术前有PVO的患者(n = 20),通过Kaplan - Meier曲线发现,L组1年和3年无死亡及术后PVO的比例分别为100%和85.7%[标准差(SD):13.2%],PT组分别为90%(SD:9.5%)和22.9%(SD:14.1%),差异有统计学意义(P = 0.002)。多变量分析显示,采用PT是死亡和术后PVO的独立危险因素(风险比4.12,95%置信区间1.12 - 15.16;P = 0.03)。
改良L形切口技术为心上型TAPVC修复提供了可接受的效果。与PT相比,改良L形切口技术与心上型梗阻性TAPVC患者死亡和术后PVO的减少显著相关。