Department of Cardiac Surgery, Union Hospital, Fujian Medical University, Fuzhou, 350001, Fujian, China.
Department of Center of Translational Medicine of Hematology, Union Hospital, Fujian Medical University, Fuzhou, Fujian, China.
Pediatr Cardiol. 2021 Jun;42(5):1002-1009. doi: 10.1007/s00246-021-02573-6. Epub 2021 Mar 23.
The efficacy of primary sutureless repair for supracardiac total anomalous pulmonary venous connection (TAPVC) needs to be confirmed. This study aimed to compare the long-term outcomes between the conventional surgery and the sutureless technique with a modified approach in superior TAPVC. Between January 2008 and December 2018, 173 patients with supracardiac TAPVC underwent surgery either with the conventional procedure (n = 130) or the sutureless repair (n = 43). Multivariate analysis and competing-risk analysis were used to identify risk factors for early death and postoperative pulmonary venous obstruction (PVO), respectively. Among 173 patients who underwent repair of supracardiac TAPVC, 46 (28%) had preoperative PVO, and 22 (12.7%) had postoperative PVO. The sutureless group had a lower postoperative PVO rate compared with the conventional group (p = 0.027). The risk factors for death were age ≤ 28 days [odds ratio (OR), 11.56; 95% confidence interval (CI) 1.33-100.47, p = 0.015], weight ≤ 3 kg (OR 9.57; 95% CI 1.58-58.09, p = 0.009), emergency operation (OR 19.24; 95% CI 3.18-116.35, p = 0.002), cardiopulmonary bypass time (OR 2.16; 95% CI 1.36-3.43, p = 0.003), cross-clamp time (OR 1.73; 95% CI 1.20-2.50, p = 0.022), and duration of ventilation (OR 1.11; 95% CI 1.02-1.21, p = 0.027). Age ≤ 28 days [Hazard Ratio (HR) 1.92; 95% CI 1.92-11.02, p < 0.001] and preoperative PVO (HR 41.70; 95% CI 8.15-213.5, p < 0.001) were associated with postoperative PVO. The sutureless repair is a reliable technique for supracardiac TAPVC. Age ≤ 28 days is associated with 30-day mortality and postoperative PVO.
经上腔静脉的心外管道矫治术(TAPVC)的原发性无缝合修复疗效尚需证实。本研究旨在比较经上腔 TAPVC 的常规手术与改良无缝合技术的长期疗效。2008 年 1 月至 2018 年 12 月,173 例 TAPVC 患者行手术治疗,其中常规手术组(n=130)和无缝合修复组(n=43)。采用多变量分析和竞争风险分析分别确定早期死亡和术后肺静脉阻塞(PVO)的危险因素。在接受经上腔 TAPVC 矫治术的 173 例患者中,术前 PVO 46 例(28%),术后 PVO 22 例(12.7%)。与常规组相比,无缝合组术后 PVO 发生率较低(p=0.027)。死亡的危险因素为年龄≤28 天[比值比(OR),11.56;95%置信区间(CI)1.33-100.47,p=0.015]、体重≤3kg(OR 9.57;95%CI 1.58-58.09,p=0.009)、急诊手术(OR 19.24;95%CI 3.18-116.35,p=0.002)、体外循环时间(OR 2.16;95%CI 1.36-3.43,p=0.003)、阻断时间(OR 1.73;95%CI 1.20-2.50,p=0.022)和通气时间(OR 1.11;95%CI 1.02-1.21,p=0.027)。年龄≤28 天[风险比(HR)1.92;95%CI 1.92-11.02,p<0.001]和术前 PVO(HR 41.70;95%CI 8.15-213.5,p<0.001)与术后 PVO 相关。经上腔 TAPVC 的无缝合修复是一种可靠的技术。年龄≤28 天与 30 天死亡率和术后 PVO 相关。