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“旋转门”现象与双相障碍:一项在急性住院病房中的回顾性研究。

"Revolving door" and Bipolar Disorders: a retrospective study in an acute inpatient unit.

机构信息

Department of Psychiatry, University of Perugia, Piazzale Lucio Severi, 1, 06132, S. Andrea delle Fratte, Perugia (PG), Italy.

出版信息

Psychiatr Danub. 2020 Sep;32(Suppl 1):58-63.

Abstract

INTRODUCTION

The present retrospective study investigated clinical correlates of the revolving door (RD) phenomenon in a population of subjects affected by Bipolar Disorders (BDs).

SUBJECTS AND METHODS

Medical records of subjects with BDs admitted to a psychiatric inpatient unit over a 5-year period of time were retrospectively reviewed and clinical data were extracted into an electronic dataset. "Revolving Door Subjects" (RDS) were defined as those who presented three or more "Revolving Door Hospitalizations" (RDH) during twelve months. Features of RDH were compared with non-RDH in order to identify characteristics associated with RD phenomenon and possible risk factors for readmission. To explore predictors of RDH, a stepwise backword logistic regression model was built, including the variables that were significantly associated with RDH in the bivariate analyses.

RESULTS

In our sample of 176 subjects affected by BDs, 53 (19.9%) RDH were identified. In the RDH group, a higher prevalence of mixed episodes (p=0.029) and medical co-morbidities (p=0.004) was detected. Subjects with repeated hospitalizations were more often committed to psychiatric residential facilities at discharge (p=0.002). Treatment features related to RDH were represented by a higher prescription rate of atypical antipsychotics (p=0.030), benzodiazepines (p=0.001) and antidepressants (p=0.048).

CONCLUSIONS

Findings from the present study suggest that the early identification and treatment of medical comorbidities and specific clinical features of BDs may help reducing the RD phenomenon in this population of subjects.

摘要

简介

本回顾性研究调查了双相情感障碍(BD)患者群体中“旋转门(RD)”现象的临床相关性。

受试者和方法

回顾性审查了在五年时间内入住精神病住院病房的 BD 受试者的医疗记录,并将临床数据提取到电子数据库中。将“旋转门受试者”(RDS)定义为在十二个月内出现三次或更多“旋转门住院”(RDH)的患者。比较 RDH 的特征,以确定与 RD 现象相关的特征和再次入院的可能危险因素。为了探索 RDH 的预测因素,建立了逐步向后逻辑回归模型,其中包括在单变量分析中与 RDH 显著相关的变量。

结果

在我们的 176 名 BD 受试者样本中,确定了 53 例(19.9%)RDH。在 RDH 组中,混合发作的患病率更高(p=0.029)和合并的医学疾病(p=0.004)。反复住院的患者在出院时更常被安置在精神科住院病房(p=0.002)。与 RDH 相关的治疗特征表现为更高的使用非典型抗精神病药(p=0.030)、苯二氮䓬类(p=0.001)和抗抑郁药(p=0.048)的处方率。

结论

本研究的结果表明,早期识别和治疗合并症以及 BD 的特定临床特征可能有助于减少该患者群体的 RD 现象。

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