Pettersson H, Ackerman N, Kaude J, Googe R E, Mancuso A A, Scott K N, Hackett R H, Hager D A, Caballero S
Acta Radiol. 1987 Jan-Feb;28(1):75-8.
An experimental series in the rabbit was performed to test gadolinium-DTPA (Gd-DTPA) enhancement of VX-2 carcinoma and hemorrhages induced in the soft tissues. The recognition of both malignant and benign lesions was greatly facilitated on T1 weighted images after intravenous administration of 0.3 mmol Gd-DTPA/kg body weight because of reduced T1 relaxation times. Gd-DTPA enhancement reached its maximum after 10-15 minutes and was most apparent in tumor tissue, connective tissue surrounding the tumor and in the area of fresh hemorrhage.
在兔身上进行了一系列实验，以测试钆喷酸葡胺（Gd-DTPA）对VX-2癌及软组织内出血的增强效果。静脉注射0.3 mmol Gd-DTPA/千克体重后，由于T1弛豫时间缩短，在T1加权图像上对恶性和良性病变的识别得到极大促进。Gd-DTPA增强在10 - 15分钟后达到最大值，在肿瘤组织、肿瘤周围的结缔组织以及新鲜出血区域最为明显。
