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血清钙在自发性颈部血肿中的重要性。

Importance of serum calcium in spontaneous neck haematoma.

机构信息

ENT, Royal Liverpool and Broadgreen Hospitals NHS Trust, Liverpool, UK

ENT, Royal Liverpool and Broadgreen Hospitals NHS Trust, Liverpool, UK.

出版信息

BMJ Case Rep. 2020 Sep 6;13(9):e237267. doi: 10.1136/bcr-2020-237267.

DOI:10.1136/bcr-2020-237267
PMID:32895253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7476466/
Abstract

We present an unusual case of spontaneous cervical haemorrhage secondary to extra-capsular bleeding from a parathyroid adenoma. Signs and symptoms on presentation included sore throat, dysphagia and anterior chest ecchymosis. While CT confirmed active cervical haemorrhage, elevated serum calcium and parathyroid hormone raised suspicion of possible parathyroid pathology. This case report and literature review highlight the diagnostic value of serum calcium in presentations of acute spontaneous neck haematoma. This should be considered especially in the acute phase, where imaging may not identify the source of haemorrhage. Initial observation and deferred surgery is the treatment of choice, with emergency operative management reserved for respiratory distress and worsening compressive symptoms.

摘要

我们报告了一例罕见的由甲状旁腺瘤包膜外出血引起的自发性颈部出血病例。就诊时的体征和症状包括咽痛、吞咽困难和前胸瘀斑。CT 证实为活动性颈部出血,血清钙和甲状旁腺激素升高提示可能存在甲状旁腺病变。本病例报告和文献复习强调了血清钙在急性自发性颈部血肿中的诊断价值。在急性阶段,影像学可能无法确定出血源,此时尤其应考虑到这一点。初始观察和延迟手术是首选治疗方法,对于有呼吸窘迫和压迫症状加重的患者,保留紧急手术治疗。

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1
Importance of serum calcium in spontaneous neck haematoma.血清钙在自发性颈部血肿中的重要性。
BMJ Case Rep. 2020 Sep 6;13(9):e237267. doi: 10.1136/bcr-2020-237267.
2
[Spontaneous cervical haematoma due to extracapsular haemorrhage of a parathyroid adenoma: a report of 2 cases].[甲状旁腺腺瘤囊外出血导致自发性颈部血肿:2例报告]
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引用本文的文献

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Spontaneous neck haemorrhage secondary to parathyroid adenoma: description of a case and systematic review.甲状旁腺腺瘤继发自发性颈部出血:一例病例描述及系统综述
Acta Otorhinolaryngol Ital. 2025 Feb;45(1):1-9. doi: 10.14639/0392-100X-N3055.
2
Atypically presented dysphagia in a patient with primary hyperparathyroidism that resolved after parathyroidectomy: A case report.原发性甲状旁腺功能亢进患者出现的非典型吞咽困难,在甲状旁腺切除术后缓解:一例报告。
Int J Surg Case Rep. 2024 Nov;124:110480. doi: 10.1016/j.ijscr.2024.110480. Epub 2024 Oct 18.

本文引用的文献

1
Spontaneous neck hematoma secondary to parathyroid adenoma: a case series.甲状旁腺腺瘤致自发性颈部血肿:病例系列研究。
Eur Arch Otorhinolaryngol. 2020 Sep;277(9):2551-2558. doi: 10.1007/s00405-020-05959-z. Epub 2020 Apr 11.
2
Spontaneous massive extracapsular haemorrhage in a parathyroid carcinoma.
Clin Endocrinol (Oxf). 2020 Jan;92(1):77-79. doi: 10.1111/cen.14113. Epub 2019 Nov 7.
3
Rare cause of acute neck hematoma.急性颈部血肿的罕见病因。
Clin Case Rep. 2019 Jun 5;7(7):1378-1381. doi: 10.1002/ccr3.2248. eCollection 2019 Jul.
4
Two cases of spontaneous remission of primary hyperparathyroidism due to auto-infarction: different management and their outcomes.两例因自梗死导致原发性甲状旁腺功能亢进自发缓解的病例:不同的处理方法及其结果
Endocrinol Diabetes Metab Case Rep. 2019 May 7;2019. doi: 10.1530/EDM-18-0136.
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Parathyroid adenoma presenting with spontaneous cervical and anterior mediastinal hemorrhage: A case report.甲状旁腺腺瘤伴自发性颈部和前纵隔出血:一例报告。
Medicine (Baltimore). 2019 Feb;98(5):e14347. doi: 10.1097/MD.0000000000014347.
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Diffuse hematoma caused by spontaneous rupture of a parathyroid adenoma: a case report.甲状旁腺腺瘤自发破裂导致弥漫性血肿:一例报告
Braz J Otorhinolaryngol. 2020 Dec;86 Suppl 1(Suppl 1):48-50. doi: 10.1016/j.bjorl.2017.06.006. Epub 2017 Jul 7.
7
Acute airway compromise due to parathyroid tumour apoplexy: an exceptionally rare and potentially life-threatening presentation.甲状旁腺肿瘤卒中导致的急性气道受压:一种极其罕见且可能危及生命的表现。
BMC Endocr Disord. 2017 Jun 21;17(1):35. doi: 10.1186/s12902-017-0186-2.
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Parathyroid Hemorrhage.
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9
Parathyroid adenoma causing spontaneous cervical hematoma: two case reports.甲状旁腺腺瘤导致自发性颈部血肿:两例报告
BMC Res Notes. 2015 Nov 26;8:726. doi: 10.1186/s13104-015-1611-0.
10
Spontaneous cervical haemorrhage of a parathyroid adenoma.甲状旁腺腺瘤自发性颈部出血。
Endocrinol Diabetes Metab Case Rep. 2015;2015:150034. doi: 10.1530/EDM-15-0034. Epub 2015 Jun 1.