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为急性冠状动脉综合征患者提供以患者为中心的护理的成本效益建模。

Modelling the cost-effectiveness of person-centred care for patients with acute coronary syndrome.

机构信息

Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Box 457, 405 30, Gothenburg, Sweden.

Centre for Person-Centred Care (GPCC), University of Gothenburg, Gothenburg, Sweden.

出版信息

Eur J Health Econ. 2020 Dec;21(9):1317-1327. doi: 10.1007/s10198-020-01230-8. Epub 2020 Sep 7.

Abstract

BACKGROUND

Person-centred care has been shown to be cost-effective compared to usual care for several diseases, including acute coronary syndrome, in a short-term time perspective (< 2 years). The cost-effectiveness of person-centred care in a longer time perspective is largely unknown.

OBJECTIVES

To estimate the mid-term cost-effectiveness of person-centred care compared to usual care for patients (< 65) with acute coronary syndrome, using a 2-year and a 5-year time perspective.

METHODS

The mid-term cost-effectiveness of person-centred care compared to usual care was estimated by projecting the outcomes observed in a randomized-controlled trial together with data from health registers and data from the scientific literature, 3 years beyond the 2-year follow-up, using the developed simulation model. Probabilistic sensitivity analyses were performed using Monte Carlo simulation.

RESULTS

Person-centred care entails lower costs and improved effectiveness as compared to usual care, for a 2-year time and a 5-year perspective. Monte Carlo simulations suggest that the likelihoods of the person-centred care being cost-effective compared to usual care were between 80 and 99% and between 75 and 90% for a 2-year and a 5-year time perspective (using a 500,000 SEK/QALY willingness-to-pay threshold).

CONCLUSIONS

Person-centred care was less costly and more effective compared to usual care in a 2-year and a 5-year time perspective for patients with acute coronary syndrome under the age of 65.

摘要

背景

与常规护理相比,以患者为中心的护理在短期时间内(<2 年)对多种疾病(包括急性冠状动脉综合征)具有成本效益。以患者为中心的护理在较长时间内的成本效益在很大程度上是未知的。

目的

从 2 年和 5 年的时间角度估计急性冠状动脉综合征患者(<65 岁)接受以患者为中心的护理与常规护理相比的中期成本效益。

方法

通过将随机对照试验中观察到的结果与健康登记数据和科学文献中的数据相结合,使用开发的模拟模型,将时间延长至 2 年随访后 3 年,估计以患者为中心的护理与常规护理相比的中期成本效益。使用蒙特卡罗模拟进行概率敏感性分析。

结果

与常规护理相比,以患者为中心的护理在 2 年和 5 年的时间内具有更低的成本和更高的效果。蒙特卡罗模拟表明,与常规护理相比,以患者为中心的护理在 2 年和 5 年的时间内具有成本效益的可能性分别在 80%到 99%之间和 75%到 90%之间(使用 500,000 瑞典克朗/QALY 的意愿支付阈值)。

结论

对于年龄在 65 岁以下的急性冠状动脉综合征患者,与常规护理相比,以患者为中心的护理在 2 年和 5 年的时间内更具成本效益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f6a/7581585/09d56e6e16b9/10198_2020_1230_Fig1_HTML.jpg

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