人静脉注射用免疫球蛋白在兽医临床实践中的应用。
Use of Human Intravenous Immunoglobulin in Veterinary Clinical Practice.
机构信息
Animal Specialty Emergency Center, 1535 South Sepulveda, Los Angeles, CA 90025, USA.
510 East 62nd Street, New York, NY 10065, USA.
出版信息
Vet Clin North Am Small Anim Pract. 2020 Nov;50(6):1371-1383. doi: 10.1016/j.cvsm.2020.07.015.
Therapy with human intravenous immunoglobulin (hIVIG) as an immunomodulator in veterinary patients results in effective but transient immunosuppression, and may be viable as part of a multidrug strategy against immune-mediated thrombocytopenia and autoimmune cutaneous disease. Efficacy of hIVIG against other veterinary autoimmune diseases is questionable. Veterinary patients tolerate hIVIG therapy well, with few infusion reactions documented. Veterinary clinical trials of hIVIG are limited, and more work is needed to determine the true efficacy and risk of hIVIG administration in companion animals.
用人类静脉注射免疫球蛋白（hIVIG）作为免疫调节剂治疗兽医患者可有效但短暂地抑制免疫，作为治疗免疫介导性血小板减少症和自身免疫性皮肤病的多药治疗策略的一部分可能是可行的。hIVIG 治疗其他兽医自身免疫性疾病的疗效尚不确定。兽医患者对 hIVIG 治疗的耐受性良好，很少有记录到输注反应。兽医中 hIVIG 的临床试验有限，需要做更多的工作来确定在伴侣动物中给予 hIVIG 的真实疗效和风险。
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