Steffens J, Nagel R
Department of Urology, Free University of Berlin, Charlottenburg Hospital, West Germany.
Br J Urol. 1988 Apr;61(4):277-83. doi: 10.1111/j.1464-410x.1988.tb13957.x.
A study was made of 170 patients with renal pelvis or ureteric tumours, 160 of whom underwent surgery between 1948 and 1981. The most important aetiological factor was chronic phenacetin abuse: 21.7% of 83 patients with renal pelvis tumours and 11.4% of those with ureteric tumours gave a history of phenacetin abuse. The latency periods ranged from 24 to 26 years. This is the first report of a relationship between abuse of analgesics and urothelial tumours from the Federal Republic of Germany.