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电子快速体能评估鉴定根治性膀胱切除术术后早期不良转归的相关因素。

Electronic Rapid Fitness Assessment Identifies Factors Associated with Adverse Early Postoperative Outcomes following Radical Cystectomy.

机构信息

Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.

Department of Epidemiology-Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.

出版信息

J Urol. 2021 Feb;205(2):400-406. doi: 10.1097/JU.0000000000001360. Epub 2020 Sep 8.

Abstract

PURPOSE

Frailty is associated with adverse outcomes following radical cystectomy. Prospective tools to identify factors affecting outcomes are needed. We describe a novel electronic rapid fitness assessment to evaluate geriatric patients undergoing radical cystectomy.

MATERIALS AND METHODS

Before undergoing radical cystectomy between February 2015 and February 2018, 80 patients older than age 75 years completed the electronic rapid fitness assessment and were perioperatively comanaged by the Geriatrics Service. Physical function and cognitive function over 12 domains were evaluated and an accumulated geriatric deficit score was compiled. Hospital length of stay, discharge disposition, unplanned intensive care unit admissions, urgent care visits, readmissions, complications and deaths were assessed.

RESULTS

A total of 65 patients who underwent radical cystectomy for bladder cancer without concomitant procedures completed the assessment. Median age was 80 (77, 84) years and 52 (80%) were male. A higher proportion of patients with intensive care unit admission, urgent care visit and major complications had impairments identified within electronic rapid fitness assessment domains, including Timed Up and Go. Readmission rates were similar between patients with or without deficits identified. Higher accumulated geriatric deficit score was significantly associated with intensive care unit admission (p=0.035), death within 90 days (p=0.037) and discharge to other than home (p=0.0002).

CONCLUSIONS

We demonstrated the feasibility of assessing fitness in patients older than 75 years undergoing radical cystectomy using a novel electronic fitness tool. Physical limitations and overall impairment corresponded to higher intensive care unit admission rates and adverse postoperative outcomes. Larger studies in less resourced environments are required to validate these findings.

摘要

目的

虚弱与根治性膀胱切除术(radical cystectomy)后的不良结局相关。需要有前瞻性的工具来识别影响结局的因素。我们描述了一种新的电子快速体能评估方法,用于评估接受根治性膀胱切除术的老年患者。

材料和方法

2015 年 2 月至 2018 年 2 月期间,80 名年龄大于 75 岁的患者在接受根治性膀胱切除术之前完成了电子快速体能评估,并由老年科团队进行了围手术期联合管理。评估了 12 个领域的身体功能和认知功能,并编制了累积老年缺陷评分。评估了住院时间、出院去向、非计划性入住重症监护病房、紧急护理就诊、再入院、并发症和死亡情况。

结果

共有 65 名接受根治性膀胱切除术治疗膀胱癌且无合并症的患者完成了评估。患者的中位年龄为 80(77,84)岁,52 名(80%)为男性。在电子快速体能评估领域,包括计时起立行走测试(Timed Up and Go),入住重症监护病房、紧急护理就诊和发生重大并发症的患者中,有更多的患者存在功能障碍。有无缺陷识别的患者的再入院率相似。较高的累积老年缺陷评分与入住重症监护病房(p=0.035)、90 天内死亡(p=0.037)和出院至非家庭(p=0.0002)显著相关。

结论

我们证明了使用新的电子体能工具评估 75 岁以上接受根治性膀胱切除术的患者体能的可行性。体能受限和总体损伤与更高的重症监护病房入住率和术后不良结局相关。需要在资源较少的环境中进行更大规模的研究来验证这些发现。

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