Department of Surgery, Memorial Sloan Kettering Cancer Center, United States.
Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, United States.
Eur J Surg Oncol. 2022 Jun;48(6):1427-1432. doi: 10.1016/j.ejso.2022.02.023. Epub 2022 Mar 11.
Retrospective studies have shown the beneficial impact of geriatric comanagement (GERICO) on perioperative outcomes of older adults with cancer. We prospectively assessed the feasibility of perioperative GERICO for older adults with bladder cancer undergoing radical cystectomy.
We conducted a pilot study wherein all patients 75 years and older undergoing radical cystectomy between October 2019 and November 2020 were referred to the Geriatric Service preoperatively. Feasibility was defined according to the percentage of patients who received preoperative evaluation by the Geriatrics Service, who were followed for more than 80% of their inpatient days and who had their surgery rescheduled for logistical reasons. Urology advanced practice provider (APP) satisfaction with the program was measured via an 11-item survey.
Sixty-six eligible patients underwent radical cystectomy in the stated time frame; 59 (89%; 95% confidence interval [CI], 79-97%) were referred to the Geriatric Service for evaluation. The median age of patients who had geriatric comanagement was 79 years; 40 (68%) were male. Forty-one patients (69%) were visited on at least 80% of the days in which they were not in the intensive care unit. No surgeries were rescheduled for logistical reasons. Nine of the 12 urology APPs (75%) responded to the survey; all nine "somewhat" or "strongly" agreed with statements indicating satisfaction with the program.
Despite the challenges of the COVID-19 pandemic, we showed that perioperative GERICO is feasible. Fully powered prospective randomized controlled trials should be conducted to assess GERICO's impact on perioperative outcomes of older adults with cancer.
回顾性研究表明,老年共管理(GERICO)对老年癌症患者围手术期结局有有益影响。我们前瞻性评估了对接受根治性膀胱切除术的老年膀胱癌患者进行围手术期 GERICO 的可行性。
我们进行了一项试点研究,其中 2019 年 10 月至 2020 年 11 月期间所有 75 岁及以上接受根治性膀胱切除术的患者均在术前转至老年科。可行性根据接受老年科术前评估的患者百分比、在住院期间超过 80%的天数接受随访的患者百分比以及因后勤原因而重新安排手术的患者百分比来定义。通过 11 项项调查来衡量泌尿科高级实践提供者(APP)对该计划的满意度。
在规定的时间范围内,有 66 名符合条件的患者接受了根治性膀胱切除术;其中 59 名(89%;95%置信区间 [CI],79-97%)被转至老年科进行评估。接受老年共管理的患者的中位年龄为 79 岁;其中 40 名(68%)为男性。41 名患者(69%)在非重症监护病房的至少 80%天数接受了探访。没有因后勤原因而重新安排手术。12 名泌尿科 APP 中有 9 名(75%)对调查做出了回应;所有人均“有些”或“非常”同意表明对该计划满意的说法。
尽管受到 COVID-19 大流行的挑战,但我们表明围手术期 GERICO 是可行的。应进行充分的前瞻性随机对照试验,以评估 GERICO 对老年癌症患者围手术期结局的影响。