Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
Univ. Bordeaux, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, F-33000 Bordeaux, France; Inserm, Centre de Recherche Cardio-Thoracique de Bordeaux, U1045, CIC 1401, F-33000 Bordeaux, France; CHU de Bordeaux, Service d'Imagerie Thoracique et Cardiovasculaire, Service des Maladies Respiratoires, Service d'Exploration Fonctionnelle Respiratoire, CIC 1401, F-33600 Pessac, France.
Magn Reson Imaging. 2020 Dec;74:64-73. doi: 10.1016/j.mri.2020.09.006. Epub 2020 Sep 6.
To investigate three MR pulse sequences under high-frequency noninvasive ventilation (HF-NIV) at 3 T and determine which one is better-suited to visualize the lung parenchyma.
A 3D ultra-short echo time stack-of spirals Volumetric Interpolated Breath-hold Examination (UTE Spiral VIBE), without and with prospective gating, and a 3D double-echo UTE sequence with spiral phyllotaxis trajectory (3D radial UTE) were performed at 3 T in ten healthy volunteers under HF-NIV. Three experienced radiologists evaluated visibility and sharpness of normal anatomical structures, artifacts assessment, and signal and contrast ratio computation. The median of the three readers'scores was used for comparison, p < .05 was considered statistically significant. Incidental findings were recorded and reported.
The 3D radial UTE resulted in less artifacts than the non-gated and gated UTE Spiral VIBE in inferior (score = 3, slight artifact without blurring vs. score = 2, moderate artifact with blurring of anatomical structure, p = .018 and p = .047, respectively) and superior lung regions (score = 3, vs. score = 2.5, p = .48 and score = 1, severe artifact with no normal structure recognizable, p = .014), and higher signal and contrast ratios (p = .002, p = .093). UTE Spiral VIBE sequences provided higher peripheral vasculature visibility than the 3D radial UTE (94.4% vs 80.6%, respectively, p < .001). The HF-NIV was well tolerated by healthy volunteers who reported on average minor discomfort. In three volunteers, 12 of 18 nodules confirmed with low-dose CT were identified with MRI (average size 2.6 ± 1.2 mm).
The 3D radial UTE provided higher image quality than the UTE Spiral VIBE. Nevertheless, a better nodule assessment was noticed with the UTE Spiral VIBE that might be due to better peripheral vasculature visibility, and requires confirmation in a larger cohort.
在 3T 高频无创通气（HF-NIV）下研究三种 MR 脉冲序列，并确定哪种更适合可视化肺实质。
在 10 名健康志愿者中，在 HF-NIV 下，对 3D 超短回波时间螺旋容积内插屏气检查（UTE 螺旋 VIBE）、无前瞻性门控和带前瞻性门控的 UTE 序列以及 3D 双回波 UTE 序列（3D 径向 UTE）进行了 3T 扫描。三位有经验的放射科医生评估了正常解剖结构的可见性和锐度、伪影评估以及信号和对比比的计算。三位读者评分的中位数用于比较，p <.05 认为具有统计学意义。记录并报告偶然发现。
与非门控和门控 UTE 螺旋 VIBE 相比，3D 径向 UTE 在下方（评分=3，轻微伪影无模糊与评分=2，中度伪影与解剖结构模糊，p=.018 和 p=.047，分别）和上肺区域（评分=3，与评分=2.5，p=.48 和评分=1，严重伪影无正常结构可识别，p=.014）的伪影更少，信号和对比比更高（p=.002，p=.093）。UTE 螺旋 VIBE 序列提供的外周血管可视性高于 3D 径向 UTE（分别为 94.4%和 80.6%，p <.001）。HF-NIV 被健康志愿者耐受良好，平均报告有轻微不适。在 3 名志愿者中，18 个结节中有 12 个经低剂量 CT 证实，MRI 可识别（平均大小 2.6±1.2mm）。
3D 径向 UTE 提供的图像质量优于 UTE 螺旋 VIBE。然而，UTE 螺旋 VIBE 注意到更好的结节评估，这可能是由于更好的外周血管可视性，需要在更大的队列中确认。
