• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

药物依赖且患有睡眠障碍患者中双重诊断的相关性。

The Relevance of Dual Diagnoses among Drug-Dependent Patients with Sleep Disorders.

作者信息

Roncero Carlos, García-Ullán Llanyra, Bullón Alberto, Remón-Gallo Diego, Vicente-Hernández Begoña, Álvarez Ana, Caldero Amaya, Flores Andrea, Aguilar Lourdes

机构信息

Psychiatry Service, University of Salamanca Health Care Complex, Paseo de San Vicente 58-182, 37007 Salamanca, Spain.

Psychiatry Unit, School of Medicine, University of Salamanca, Campus Miguel de Unamuno C/ Alfonso X El Sabio s/n, 37007 Salamanca, Spain.

出版信息

J Clin Med. 2020 Sep 4;9(9):2862. doi: 10.3390/jcm9092862.

DOI:10.3390/jcm9092862
PMID:32899692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7565704/
Abstract

BACKGROUND

Sleep disorders are often associated with drug use. Nearly 70% of patients admitted for detoxification report sleep problems. Dual disorder (DD) is the comorbidity between mental disorders in general and disorders related to psychoactive substance use. The association between substance use and sleep disorders (SD) appears to be bidirectional. Our objective is to analyze the association between sleep disturbance history and drug use pattern (alcohol, cannabis, opioids, and cocaine).

METHODS

Analysis of data in the first interview at the Addictions Unit of the Department of Psychiatry at the University of Salamanca Health Care Complex between October 2017 and January 2020. The sample consists of 398 patients. We studied the association between different variables: origin of patients (Inpatient Dual Diagnosis Detoxification Unit (IDDDU) vs. Outpatient Drug Clinic (ODC), presence of affective disorder, psychotic disorder, type of drug used, and treatment.

RESULTS

Of patients with DD, 62% had more delayed sleep induction, sleep fragmentation, early awakening, and nightmares. Outpatients had more difficulty falling asleep because, in many cases, they had not previously sought any medical assistance. On the other hand, 67% of the patients with insomnia presented depression.

CONCLUSIONS

There is evidence of a harmful association between DD and SD.

摘要

背景

睡眠障碍常与药物使用相关。近70%因戒毒入院的患者报告存在睡眠问题。双重障碍(DD)是一般精神障碍与精神活性物质使用相关障碍之间的共病情况。物质使用与睡眠障碍(SD)之间的关联似乎是双向的。我们的目的是分析睡眠障碍史与药物使用模式(酒精、大麻、阿片类药物和可卡因)之间的关联。

方法

对2017年10月至2020年1月期间萨拉曼卡大学医疗中心精神病学系成瘾科首次访谈中的数据进行分析。样本包括398名患者。我们研究了不同变量之间的关联:患者来源(住院双重诊断戒毒单元(IDDDU)与门诊药物诊所(ODC))、情感障碍的存在、精神障碍、使用的药物类型和治疗情况。

结果

在双重障碍患者中,62%的患者入睡延迟、睡眠碎片化、早醒和噩梦情况更严重。门诊患者入睡困难更多,因为在很多情况下,他们之前未曾寻求过任何医疗帮助。另一方面,67%的失眠患者存在抑郁症状。

结论

有证据表明双重障碍与睡眠障碍之间存在有害关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efb7/7565704/d2acd9acde8a/jcm-09-02862-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efb7/7565704/d2acd9acde8a/jcm-09-02862-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efb7/7565704/d2acd9acde8a/jcm-09-02862-g001.jpg

相似文献

1
The Relevance of Dual Diagnoses among Drug-Dependent Patients with Sleep Disorders.药物依赖且患有睡眠障碍患者中双重诊断的相关性。
J Clin Med. 2020 Sep 4;9(9):2862. doi: 10.3390/jcm9092862.
2
[Dual diagnosis in psychoactive substance abusing or dependent persons].[精神活性物质滥用或依赖者的双重诊断]
Psychiatr Pol. 2013 Mar-Apr;47(2):335-52.
3
[Dual diagnosis in psychiatric inpatients: prevalence and general characteristics].[精神科住院患者的双重诊断:患病率及一般特征]
Invest Clin. 2008 Jun;49(2):195-205.
4
Sleep complaints among the elderly: results from a survey in a psychogeriatric outpatient clinic in Brazil.
Int Psychogeriatr. 1999 Mar;11(1):47-56. doi: 10.1017/s1041610299005578.
5
[Effect of comorbid substance use on neuropsychological performance in subjects with psychotic or mood disorders].[共病物质使用对患有精神病性或心境障碍的受试者神经心理表现的影响]
Encephale. 2002 Mar-Apr;28(2):160-8.
6
Insomnia Symptoms in Patients With Substance Use Disorders During Detoxification and Associated Clinical Features.物质使用障碍患者戒毒期间的失眠症状及相关临床特征
Front Psychiatry. 2020 Nov 17;11:540022. doi: 10.3389/fpsyt.2020.540022. eCollection 2020.
7
Multiple drug use and psychiatric comorbidity in patients admitted to the hospital with severe benzodiazepine dependence.因严重苯二氮䓬类药物依赖而入院的患者中的多药使用与精神疾病共病情况
J Clin Psychopharmacol. 1996 Feb;16(1):51-7. doi: 10.1097/00004714-199602000-00009.
8
[Etiology of adult insomnia].[成人失眠的病因]
Encephale. 2002 Nov-Dec;28(6 Pt 1):493-502.
9
[Which psychiatric comorbidities in cannabis dependence during adolescence? Comparison of outpatients and controls].[青少年大麻依赖中的哪些精神共病?门诊患者与对照组的比较]
Encephale. 2018 Feb;44(1):2-8. doi: 10.1016/j.encep.2016.05.013. Epub 2016 Sep 13.
10
[A connection between insomnia and psychiatric disorders in the French general population].[法国普通人群中失眠与精神障碍之间的联系]
Encephale. 2002 Sep-Oct;28(5 Pt 1):420-8.

引用本文的文献

1
Objective and subjective measurement of sleep in people who use substances: Emerging evidence and recommendations from a systematic review.物质使用者睡眠的客观与主观测量:系统评价的新证据与建议
J Sleep Res. 2025 Apr;34(2):e14330. doi: 10.1111/jsr.14330. Epub 2024 Sep 5.
2
Gender differences in sleep quality among Iranian traditional and industrial drug users.伊朗传统药物使用者与工业药物使用者睡眠质量的性别差异。
Neurobiol Sleep Circadian Rhythms. 2024 Jul 2;17:100104. doi: 10.1016/j.nbscr.2024.100104. eCollection 2024 Nov.
3
Changes in substance use and engagement in gaming/gambling in persons with severe mental illness during the COVID-19 pandemic and earthquakes: a community study in two points.

本文引用的文献

1
Management of insomnia in alcohol use disorder.酒精使用障碍相关失眠的管理。
Expert Opin Pharmacother. 2020 Feb;21(3):297-306. doi: 10.1080/14656566.2019.1705279. Epub 2020 Jan 3.
2
Alterations in circadian rhythms following alcohol use: A systematic review.饮酒后昼夜节律的改变:一项系统综述。
Prog Neuropsychopharmacol Biol Psychiatry. 2020 Apr 20;99:109831. doi: 10.1016/j.pnpbp.2019.109831. Epub 2019 Dec 3.
3
Benzodiazepine abuse, misuse, dependence, and withdrawal among schizophrenic patients: A review of the literature.
新冠疫情和地震期间重度精神疾病患者的物质使用及游戏/赌博行为变化:两点社区研究
Front Psychiatry. 2023 Dec 15;14:1264875. doi: 10.3389/fpsyt.2023.1264875. eCollection 2023.
4
Circadian rhythmicity in schizophrenia male patients with and without substance use disorder comorbidity.精神分裂症男性患者伴或不伴物质使用障碍共病的昼夜节律性。
Eur Arch Psychiatry Clin Neurosci. 2024 Mar;274(2):279-290. doi: 10.1007/s00406-023-01560-7. Epub 2023 Mar 6.
5
Interaction between cocaine use and sleep behavior: A comprehensive review of cocaine's disrupting influence on sleep behavior and sleep disruptions influence on reward seeking.可卡因使用与睡眠行为的相互作用:可卡因对睡眠行为的破坏作用以及睡眠紊乱对寻求奖赏的影响的综合综述。
Pharmacol Biochem Behav. 2021 Jul;206:173194. doi: 10.1016/j.pbb.2021.173194. Epub 2021 May 1.
6
Special Issue: Diagnosis and Management of Addiction and Other Mental Disorders (Dual Disorders).特刊:成瘾及其他精神障碍(双重障碍)的诊断与管理
J Clin Med. 2021 Mar 22;10(6):1307. doi: 10.3390/jcm10061307.
苯二氮䓬类药物滥用、误用、依赖和精神分裂症患者的戒断:文献综述。
Psychiatry Res. 2020 Feb;284:112660. doi: 10.1016/j.psychres.2019.112660. Epub 2019 Oct 28.
4
[Should the duration of treatment be limited using benzodiazepines?].使用苯二氮䓬类药物时治疗时长应受限吗?
Presse Med. 2018 Oct;47(10):892-898. doi: 10.1016/j.lpm.2018.10.006. Epub 2018 Oct 25.
5
Pharmacological Treatment of Insomnia Symptoms in Individuals with Substance Use Disorders in Spain: A Quasi-Experimental Study.西班牙物质使用障碍患者失眠症状的药物治疗:一项准实验研究。
Subst Use Misuse. 2018 Jul 3;53(8):1267-1274. doi: 10.1080/10826084.2017.1402056. Epub 2017 Nov 29.
6
Dual diagnosis: an European perspective.双重诊断:欧洲视角。
Adicciones. 2017 Jan 1;29(1):3-5. doi: 10.20882/adicciones.933.
7
Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review.与酒精、大麻、可卡因和阿片类药物使用相关的睡眠异常:一项综合综述。
Addict Sci Clin Pract. 2016 Apr 26;11(1):9. doi: 10.1186/s13722-016-0056-7.
8
Administrative prevalence of insomnia and associated clinical features in patients with addiction during active substance use.在活跃物质使用期间成瘾患者中失眠的管理患病率及相关临床特征。
Actas Esp Psiquiatr. 2016 Mar-Apr;44(2):64-71. Epub 2016 Mar 1.
9
Modafinil and sleep architecture in an inpatient-outpatient treatment study of cocaine dependence.莫达非尼对可卡因依赖患者住院-门诊治疗的睡眠结构的影响
Drug Alcohol Depend. 2016 Mar 1;160:49-56. doi: 10.1016/j.drugalcdep.2015.12.004. Epub 2016 Jan 8.
10
Sleep, alcohol and alcohol abuse.睡眠、酒精与酒精滥用。
Addict Biol. 1997 Apr;2(2):151-8. doi: 10.1080/13556219772697.