Veyseh Maedeh, Pophali Prateek, Jayarangaiah Apoorva, Kumar Abhishek
Medicine, Jacobi Medical Center, Bronx, New York, USA.
Hematology and Oncology, Jacobi Medical Center, Bronx, New York, USA.
BMJ Case Rep. 2020 Sep 7;13(9):e236786. doi: 10.1136/bcr-2020-236786.
COVID-19 disease is a viral illness that predominantly causes pneumonia and severe acute respiratory distress syndrome. The endothelial injury and hypercoagulability secondary to the inflammatory response predisposes severely ill patients to venous thromboembolism. The exact mechanism of hypercoagulability is still under investigation, but it is known to be associated with poor prognosis. The most common thrombotic complication reported among these patients is pulmonary embolism. To our knowledge, gonadal vein thrombosis is an uncommon phenomenon that has not been reported in the setting of COVID-19-associated coagulopathy. We report an unusual case of ovarian vein thrombosis and pulmonary embolism associated with COVID-19 presenting with abdominal pain. To our knowledge, this is the first reported case of COVID-19 with absent respiratory symptoms and presentation with venous thrombosis in an unusual location.
新型冠状病毒肺炎(COVID-19)是一种病毒性疾病,主要引起肺炎和严重急性呼吸窘迫综合征。炎症反应继发的内皮损伤和高凝状态使重症患者易发生静脉血栓栓塞。高凝的确切机制仍在研究中,但已知与预后不良有关。这些患者中报告的最常见血栓并发症是肺栓塞。据我们所知,性腺静脉血栓形成是一种罕见现象,在COVID-19相关凝血病中尚未见报道。我们报告一例与COVID-19相关的卵巢静脉血栓形成和肺栓塞的罕见病例,患者表现为腹痛。据我们所知,这是首例报告的无呼吸道症状、而在不寻常部位出现静脉血栓形成的COVID-19病例。