Klaus G G
National Institute for Medical Research, Mill Hill, London, U.K.
Immunol Suppl. 1988;1:35-7.
The responses of B cells to specific antigens are modulated by secondary signals delivered by a variety of cell surface receptors. Besides surface immunoglobulins, these include class II MHC antigens, Fc and C3 receptors, in addition to those for various lymphokines. The current knowledge of the second messengers used by various receptors and their roles in B-cell activation are discussed here.
B细胞对特定抗原的反应受到多种细胞表面受体传递的第二信号的调节。除了表面免疫球蛋白外,这些受体还包括II类MHC抗原、Fc和C3受体,以及各种淋巴因子的受体。本文讨论了各种受体使用的第二信使及其在B细胞活化中的作用的当前知识。