对“心力衰竭中兰尼碱受体2功能障碍的机制”的回复 - Suppr | 超能文献

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Reply to 'Mechanisms of ryanodine receptor 2 dysfunction in heart failure'.对“心力衰竭中兰尼碱受体2功能障碍的机制”的回复

Nat Rev Cardiol. 2020 Nov;17(11):749-750. doi: 10.1038/s41569-020-00444-w.

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Mechanisms of ryanodine receptor 2 dysfunction in heart failure.心力衰竭中兰尼碱受体2功能障碍的机制。

Nat Rev Cardiol. 2020 Nov;17(11):748. doi: 10.1038/s41569-020-00443-x.

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Stabilizing ryanodine receptor gating quiets arrhythmogenic events in human heart failure and atrial fibrillation.稳定兰尼碱受体门控可减少人类心力衰竭和心房颤动中的致心律失常事件。

Heart Rhythm. 2017 Mar;14(3):420-421. doi: 10.1016/j.hrthm.2016.10.005. Epub 2016 Oct 7.

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Down-regulation of L-type calcium channel and sarcoplasmic reticular Ca(2+)-ATPase mRNA in human atrial fibrillation without significant change in the mRNA of ryanodine receptor, calsequestrin and phospholamban: an insight into the mechanism of atrial electrical remodeling.人类心房颤动中L型钙通道和肌浆网Ca(2+)-ATP酶mRNA下调，而雷诺丁受体、肌集钙蛋白和受磷蛋白的mRNA无显著变化：对心房电重构机制的深入了解

J Am Coll Cardiol. 1999 Apr;33(5):1231-7. doi: 10.1016/s0735-1097(99)00008-x.

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Targeting pathological leak of ryanodine receptors: preclinical progress and the potential impact on treatments for cardiac arrhythmias and heart failure.靶向兰尼碱受体病理性释放：临床前进展及其对心律失常和心力衰竭治疗的潜在影响。

Expert Opin Ther Targets. 2020 Jan;24(1):25-36. doi: 10.1080/14728222.2020.1708326. Epub 2020 Jan 3.

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The cardiac ryanodine receptor (calcium release channel): emerging role in heart failure and arrhythmia pathogenesis.心肌兰尼碱受体（钙释放通道）：在心力衰竭和心律失常发病机制中的新作用。

Cardiovasc Res. 2002 Dec;56(3):359-72. doi: 10.1016/s0008-6363(02)00574-6.

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Calcium-mediated cellular triggered activity in atrial fibrillation.钙介导的心房颤动细胞触发活动。

J Physiol. 2017 Jun 15;595(12):4001-4008. doi: 10.1113/JP273048. Epub 2017 Mar 22.

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S4153R is a gain-of-function mutation in the cardiac Ca(2+) release channel ryanodine receptor associated with catecholaminergic polymorphic ventricular tachycardia and paroxysmal atrial fibrillation.S4153R 是心脏 Ca(2+)释放通道 Ryanodine 受体的功能获得性突变，与儿茶酚胺多形性室性心动过速和阵发性心房颤动有关。

Can J Cardiol. 2013 Aug;29(8):993-6. doi: 10.1016/j.cjca.2012.12.019. Epub 2013 Mar 13.

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Junctophilin-2 expression rescues atrial dysfunction through polyadic junctional membrane complex biogenesis.连接蛋白-2 的表达通过多联体连接膜复合物体的生成来挽救心房功能障碍。

JCI Insight. 2019 Jun 20;4(12). doi: 10.1172/jci.insight.127116.

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Holiday Heart Syndrome, Atrial Fibrillation, and RyR2 Antagonist.假日心脏综合征、心房颤动和 RyR2 拮抗剂。

J Cardiovasc Pharmacol. 2022 Nov 1;80(5):636-638. doi: 10.1097/FJC.0000000000001352.

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Preventing the phosphorylation of RyR2 at canonical sites reduces Ca leak and promotes arrhythmia by reactivating the I current.阻止兰尼碱受体2（RyR2）在典型位点的磷酸化可减少钙泄漏，并通过重新激活I电流促进心律失常。

Nat Cardiovasc Res. 2025 Aug;4(8):976-990. doi: 10.1038/s44161-025-00693-3. Epub 2025 Aug 12.

2

Long non-coding RNA and circular RNA: new perspectives for molecular pathophysiology of atrial fibrillation.长链非编码RNA与环状RNA：心房颤动分子病理生理学的新视角

Mol Biol Rep. 2023 Mar;50(3):2835-2845. doi: 10.1007/s11033-022-08216-0. Epub 2023 Jan 4.

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Preserved cardiac performance and adrenergic response in a rabbit model with decreased ryanodine receptor 2 expression.