Hailay Abrha, Aberhe Woldu, Zereabruk Kidane, Mebrahtom Guesh, Haile Teklehaimanot, Bahrey Degena, Mariye Teklewoini
Department of Adult health Nursing, School of Nursing, Aksum University, Aksum, Ethiopia.
Department of Maternity and Neonatal Nursing, School of Nursing, Aksum University, Aksum, Ethiopia.
Asthma Res Pract. 2020 Sep 4;6:8. doi: 10.1186/s40733-020-00061-x. eCollection 2020.
Coronavirus disease 2019 outbreak is the first reported case in Wuhan, China in December 2019 and suddenly became a major global health concern. According to the European Centre for Disease Prevention and Control, on August 4, 2020 the reported cases of coronavirus disease 2019 were 18,456,952 cases worldwide, 11,691,229 recovered with 697,719 deaths. Evidence on Burden, admission and outcome of Coronavirus Disease in 2019 among Asthmatic patients has not been published in Africa. This research protocol will, therefore, be driven to conduct systematic review and meta-analysis of the Coronavirus Disease in 2019 burden, admission and outcome among Asthmatic patients in Africa.
All observational studies among Asthmatic patients in Africa and written without language limitation will be included. A search technique was applied using Databases (PubMed / MEDLINE, EMBASE, HINARI, Cochrane Library, World Health Organization COVID-19 database, Africa Wide Knowledge and Web of Science). Two independent authors carried out data extraction and assess the risk of bias using a predetermined and structured method of data collection. We will use random-effects to estimate the overall pooled burden, admission and outcome of COVID-19 Asthmatic patients in Africa. To assess possible publication bias, funnel plot test and Egger's test methods will be used This systematic and meta-analysis review protocol will be reported based on the Preferred Reporting Items for Systematic reviews and Meta-Analysis protocol guidelines.
The description will be used to show the COVID-19 distribution data by interest variables such as residence, setting, and person-level characteristics. The findings of this review will notify health care professionals about the burden, admission and outcome of COVID - 19 in asthmatic patient, while providing evidence to bring about the requisite improvements in clinical practice for asthmatic patients.
This review is registered in the PROSPERO International Prospective Register of Systematic reviews with the registration number of CRD42020202049.
2019年冠状病毒病疫情于2019年12月在中国武汉首次报告，并突然成为全球主要的卫生问题。根据欧洲疾病预防控制中心的数据，2020年8月4日，全球报告的2019年冠状病毒病病例为18456952例，其中11691229例康复，697719例死亡。非洲尚未发表关于2019年冠状病毒病在哮喘患者中的负担、入院情况和转归的证据。因此，本研究方案将致力于对非洲哮喘患者中2019年冠状病毒病的负担、入院情况和转归进行系统评价和荟萃分析。
将纳入所有针对非洲哮喘患者的观察性研究，且不受语言限制。采用检索技术，使用数据库（PubMed / MEDLINE、EMBASE、HINARI、Cochrane图书馆、世界卫生组织COVID-19数据库、非洲广泛知识数据库和科学网）。两名独立作者进行数据提取，并使用预先确定的结构化数据收集方法评估偏倚风险。我们将使用随机效应模型来估计非洲COVID-19哮喘患者的总体合并负担、入院情况和转归。为评估可能的发表偏倚，将使用漏斗图检验和埃格检验方法。本系统评价和荟萃分析方案将根据系统评价和荟萃分析方案的首选报告项目指南进行报告。
该描述将用于按居住、环境和个人层面特征等感兴趣的变量展示COVID-19分布数据。本综述的结果将告知医护人员COVID-19在哮喘患者中的负担、入院情况和转归，同时为改善哮喘患者的临床实践提供必要证据。
本综述已在PROSPERO国际前瞻性系统评价注册库注册，注册号为CRD42020202049。
