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患有侵蚀性牙磨损儿童的唾液特征:一项横断面研究。

Salivary profile of children with erosive tooth wear: a transversal study.

作者信息

Shitsuka Caleb, Palma Luiz Felipe, Pedron Irineu Gregnanin, Polotow Tatiana Geraldo Guizelini, Barros Marcelo Paes de, Leite Mariana Ferreira, CorrÊa Maria Salete Nahás Pires

机构信息

Faculdades Metropolitanas Unidas - FMU , School of Dentistry , São Paulo , SP , Brazil .

Universidade Ibirapuera - UNIB, Graduate Dentistry Program , São Paulo , SP , Brazil .

出版信息

Braz Oral Res. 2020 Sep 4;34:e115. doi: 10.1590/1807-3107bor-2020.vol34.0115.

Abstract

The aim of the present transversal study was to evaluate the clinical and biochemical salivary parameters of children with and without erosive tooth wear (ETW). The study population was children aged 4 to 9 years. A trained and calibrated examiner (kappa value for intraexaminer reliability = 0.89) classified the children into ETW (n = 24) and control groups (n = 24), and applied the O'Brien index. The salivary flow rate was initially evaluated by stimulated sialometry (paraffin chewing). Afterwards, the collected saliva was submitted to biochemical analyses of pH, uric acid, total buffering capacity, ferric-reducing antioxidant power, reduced glutathione, calcium, and phosphorus. Among the ETW children, 20 (83%) had dental lesions restricted to enamel, and 4 (17%) presented lesions affecting both enamel and dentin. A statistically significant difference between the groups was obtained only for the pH values (t-test; p = 0.004), with averages of 7.31 and 7.56 for the control and the ETW groups, respectively. Considering the parameters evaluated in general, it is suggested that the salivary profile of children with ETW does not differ considerably from that of children without ETW. However, the pH mean value seems to be slightly higher in ETW children, but is still within the normal physiological range.

摘要

本横向研究的目的是评估患有和未患有侵蚀性牙磨损(ETW)的儿童的临床和生化唾液参数。研究对象为4至9岁的儿童。一名经过培训且校准的检查者(检查者内部可靠性的kappa值 = 0.89)将儿童分为ETW组(n = 24)和对照组(n = 24),并应用奥布赖恩指数。唾液流速最初通过刺激唾液分泌测量法(咀嚼石蜡)进行评估。之后,将收集的唾液进行pH值、尿酸、总缓冲能力、铁还原抗氧化能力、还原型谷胱甘肽、钙和磷的生化分析。在患有ETW的儿童中,20名(83%)的牙齿病变仅限于牙釉质,4名(17%)的病变累及牙釉质和牙本质。两组之间仅在pH值上存在统计学显著差异(t检验;p = 0.004),对照组和ETW组的平均值分别为7.31和7.56。总体考虑所评估的参数,提示患有ETW儿童的唾液特征与未患ETW儿童的唾液特征没有显著差异。然而,ETW儿童的pH平均值似乎略高,但仍在正常生理范围内。

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