Sernicola A, Faina V, Chello C, Di Fraia M, Gagliostro N, Muharremi R, Magri F, Grieco T
Unit of Dermatology, Department of Internal and Specialized Medicine, "Sapienza" University of Rome, Rome, Italy.
Clin Ter. 2020 Sep-Oct;171(5):e369-e370.
Skin findings are common among patients with hematological malignancies and are thought to be expressions of a reactive spectrum peculiar to immunosuppressed patients with an unclear pathogenesis. Eosinophilic panniculitis is a reaction pattern defined by single or multiple lesions consisting in nodules and plaques, and sometimes in papules and pustules, characteristically associated to hematological neoplasms or to a series of benign conditions such as arthropod bites. We report a case of eosinophilic panniculitis occurring in a 77-year-old woman with chronic lymphocytic leukemia. Our case is remarkable as the histology of panniculitis was associated with a clinical evidence of dermal papules and a history of insect bites.
皮肤表现在血液系统恶性肿瘤患者中很常见，被认为是免疫抑制患者特有的反应谱表现，其发病机制尚不清楚。嗜酸性脂膜炎是一种反应模式，由单个或多个病变组成，包括结节和斑块，有时还有丘疹和脓疱，典型地与血液系统肿瘤或一系列良性疾病如节肢动物叮咬相关。我们报告一例发生在一名77岁慢性淋巴细胞白血病女性患者身上的嗜酸性脂膜炎。我们的病例很特殊，因为脂膜炎的组织学表现与皮肤丘疹的临床证据以及昆虫叮咬史有关。
