Pediatric Skin Center, Department of Dermatology, University Children's Hospital Zurich, Zurich, Switzerland.
Pediatric Skin Center, Skin- and Wound Management, University Children's Hospital Zurich, Zurich, Switzerland.
Pediatr Dermatol. 2020 Nov;37(6):1183-1184. doi: 10.1111/pde.14356. Epub 2020 Sep 9.
We report the case of a 10-year-old girl with bullous Sweet syndrome, recalcitrant to high-dose systemic corticosteroids. Subsequent treatment with infliximab resulted in a rapid improvement in cutaneous lesions and systemic symptoms. Cutis laxa was noted in the healed skin. We propose early second-line treatment with infliximab in children with steroid-refractory Sweet syndrome.
我们报告了一例 10 岁女孩患大疱性Sweet 综合征的病例，该患者对大剂量全身皮质类固醇治疗无反应。随后使用英夫利昔单抗治疗导致皮肤病变和全身症状迅速改善。愈合皮肤出现皮肤松弛症。我们建议对类固醇难治性 Sweet 综合征患儿进行早期二线英夫利昔单抗治疗。
