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哮喘、过敏性鼻炎、特应性皮炎和食物过敏的负担和社会经济学。

Burden and socioeconomics of asthma, allergic rhinitis, atopic dermatitis and food allergy.

机构信息

Department of General Practice & Elderly Care Medicine, University of Groningen, University Medical Center Groningen , Groningen, The Netherlands.

Groningen Research Institute for Asthma and COPD (GRIAC) , Groningen, The Netherlands.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2020 Oct;20(5):437-453. doi: 10.1080/14737167.2020.1819793. Epub 2020 Sep 14.

Abstract

INTRODUCTION

Asthma, allergic rhinitis, atopic dermatitis, and food allergy affect approximately 20% of the global population. Few studies describe the burden of the totality of these diseases and only a handful studies provide a comprehensive overview of the socioeconomic impact of these diseases.

AREAS COVERED

For this narrative review, we searched Pubmed using selected keywords and inspected relevant references using a snowballing process. We provide an overview of the socioeconomic burden of allergic diseases (in particular, asthma, allergic rhinitis, atopic dermatitis, and food allergy). The focus of this review is on their epidemiology (incidence, prevalence), burden (disability-adjusted life years, quality of life), and direct and indirect costs (absenteeism and presenteeism). We have put special emphasis on differences between countries.

EXPERT COMMENTARY

Both the prevalence and the burden of allergic diseases are considerable with prevalence varying between 1% and 20%. We identified a plethora of studies on asthma, but studies were generally difficult to compare due to the heterogeneity in measures used. There were only few studies on the burden of food allergy; therefore, more studies on this allergy are required. For future studies, we recommend standardizing epidemiologic, socioeconomic impact, and quality of life measures of allergic diseases.

摘要

简介

哮喘、过敏性鼻炎、特应性皮炎和食物过敏影响了全球约 20%的人口。很少有研究描述这些疾病的整体负担,只有少数研究全面概述了这些疾病的社会经济影响。

涵盖领域

在这篇叙述性综述中,我们使用选定的关键词在 Pubmed 上进行了搜索,并使用滚雪球的方法检查了相关参考文献。我们概述了过敏性疾病(特别是哮喘、过敏性鼻炎、特应性皮炎和食物过敏)的社会经济负担。本综述的重点是它们的流行病学(发病率、患病率)、负担(伤残调整生命年、生活质量)以及直接和间接成本(旷工和在职)。我们特别强调了国家之间的差异。

专家评论

过敏性疾病的患病率和负担都相当大,患病率在 1%至 20%之间变化。我们发现了大量关于哮喘的研究,但由于使用的措施存在异质性,这些研究通常难以进行比较。关于食物过敏负担的研究很少;因此,需要对这种过敏进行更多的研究。对于未来的研究,我们建议对过敏性疾病的流行病学、社会经济影响和生活质量措施进行标准化。

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