Amsterdam UMC, Location AMC, University of Amsterdam, Department of Orthopaedic Surgery, Amsterdam Movement Sciences, Amsterdam, The Netherlands.
Academic Center for Evidence-based Sports Medicine (ACES), Amsterdam, The Netherlands.
Oper Orthop Traumatol. 2021 Apr;33(2):160-169. doi: 10.1007/s00064-020-00673-9. Epub 2020 Sep 9.
Provision of a natural scaffold, good quality cells, and growth factors in order to facilitate the replacement of the complete osteochondral unit with matching talar curvature for large medial primary and secondary osteochondral defects of the talus.
Symptomatic primary and secondary medial osteochondral defects of the talus not responding to conservative treatment; anterior-posterior or medial-lateral diameter >10 mm on computed tomography (CT); closed distal tibial physis in young patients.
Tibiotalar osteoarthritis grade III; multiple osteochondral defects on the medial, central, and lateral talar dome; malignancy; active infectious ankle joint pathology.
A medial distal tibial osteotomy is performed, after which the osteochondral defect is excised in toto from the talar dome. The recipient site is microdrilled in order to disrupt subchondral bone vessels. Then, the autograft is harvested from the ipsilateral iliac crest with an oscillating saw, after which the graft is adjusted to an exact fitting shape to match the extracted osteochondral defect and the talar morphology as well as curvature. The graft is implanted with a press-fit technique after which the osteotomy is reduced with two 3.5 mm lag screws and the incision layers are closed. In cases of a large osteotomy, an additional third tubular buttress plate is added, or a third screw at the apex of the osteotomy.
Non-weight bearing cast for 6 weeks, followed by another 6 weeks with a walking boot. After 12 weeks, a CT scan is performed to assess consolidation of the osteotomy and the inserted autograft. The patient is referred to a physiotherapist.
Ten cases underwent the TOPIC procedure, and at 1 year follow-up all clinical scores improved. Radiological outcomes showed consolidation of all osteotomies and all inserted grafts showed consolidation. Complications included one spina iliaca anterior avulsion and one hypaesthesia of the saphenous nerve; in two patients the fixation screws of the medial malleolar osteotomy were removed.
提供一个天然的支架、高质量的细胞和生长因子,以促进与距骨曲率匹配的完整的骨软骨单位的替换,用于治疗距骨的大内侧原发性和继发性骨软骨缺损。
对保守治疗无反应的症状性原发性和继发性距骨内侧骨软骨缺损;CT 上前后径或内外径>10mm;年轻患者胫骨远端骺板闭合。
距骨-跟骨关节炎 3 级;距骨内侧、中央和外侧穹隆有多发性骨软骨缺损;恶性肿瘤;活动性感染性踝关节病变。
行胫骨内侧远端切开术,然后整块切除距骨穹隆的骨软骨缺损。用微钻在受区钻孔,以破坏软骨下骨血管。然后,用摆动锯从同侧髂嵴取骨,然后将移植物调整到与所取的骨软骨缺损和距骨形态及曲率完全匹配的形状。用压配技术植入移植物,然后用 2 枚 3.5mm 拉力螺钉复位切开,关闭切口各层。对于大的切开,可加用第三根管状支撑钢板,或在切开顶点加用第三根螺钉。
非负重石膏固定 6 周,然后用步行靴固定 6 周。12 周后,行 CT 扫描评估切开和插入的自体移植物的愈合情况。患者转介给物理治疗师。
10 例患者接受了 TOPIC 手术,1 年随访时所有临床评分均改善。影像学结果显示所有切开均愈合,所有插入的移植物均愈合。并发症包括 1 例髂前棘撕脱和 1 例隐神经感觉减退;2 例患者的内踝切开固定螺钉被取出。