Virdee Jasvir, Larcombe Stephanie, Vijay Vivek, Sinclair Alex J, Dayan Margaret, Mollan Susan P
Ophthalmology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Medical School, University of Birmingham, Birmingham, UK.
Ophthalmol Ther. 2020 Dec;9(4):767-781. doi: 10.1007/s40123-020-00296-0. Epub 2020 Sep 9.
There is increasing evidence and appreciation of idiopathic intracranial hypertension (IIH) in medicine. The pathological processes underlying raised intracranial pressure are being studied, with new insights found in both hormonal dysregulation and the metabolic neuroendocrine axis. These will potentially lead to novel therapeutic targets for IIH. The first consensus guidelines have been published on the investigation and management of adult IIH, and the International Headache Society criteria for headache attributable to IIH have been modified to reflect our evolving understanding of IIH. Randomized clinical trials have been published, and a number of studies in this disease area are ongoing.
医学领域对特发性颅内高压（IIH）的证据和认识日益增加。颅内压升高背后的病理过程正在研究中，在激素失调和代谢神经内分泌轴方面都有了新的见解。这些可能会为IIH带来新的治疗靶点。关于成人IIH的调查和管理的首个共识指南已经发布，国际头痛协会关于IIH所致头痛的标准也已修改，以反映我们对IIH不断发展的认识。随机临床试验已经发表，该疾病领域的一些研究正在进行中。
