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一款用于检测白化病患者皮肤癌的智能手机应用程序的可行性研究。

Feasibility Study of a Smartphone Application for Detecting Skin Cancers in People With Albinism.

作者信息

Rubagumya Fidel, Nyagabona Sarah K, Longombe Ahuka N, Manirakiza Achille, Ngowi John, Maniragaba Theoneste, Sabushimike Doriane, Urusaro Sandra, Ndoli Diane A, Dharsee Nazima, Mwaiselage Julius, Mavura Daudi, Hanna Timothy P, Hammad Nazik

机构信息

Department of Oncology, Rwanda Military Hospital, Kigali, Rwanda.

University of Global Health Equity, Burera, Rwanda.

出版信息

JCO Glob Oncol. 2020 Sep;6:1370-1375. doi: 10.1200/GO.20.00264.

Abstract

PURPOSE

Albinism affects some facets of the eye's function and coloration, as well as hair and skin color. The prevalence of albinism is estimated to be one in 2,000-5,000 people in sub-Saharan Africa and one in 270 in Tanzania. People in Tanzania with albinism experience sociocultural and economic disparities. Because of stigma related to albinism, they present to hospitals with advanced disease, including skin cancers. Mobile health (mHealth) can help to bridge some of the gaps in detection and treatment of skin cancers affecting this population.

METHODS

We assessed the feasibility of using a mobile application (app) for detection of skin cancers among people with albinism. The study was approved by the Ocean Road Cancer Institute institutional review board. Data, including pictures of the lesions, were collected using a mobile smartphone and submitted to expert reviewers. Expert reviewers' diagnosis options were benign, malignant, or unevaluable.

RESULTS

A total of 77 lesions from different body locations of 69 participants were captured by the NgoziYangu mobile app. Sixty-two lesions (81%) were considered malignant via the app and referred for biopsy and histologic diagnosis. Of those referred, 55 lesions (89%) were biopsied, and 47 lesions (85%) were confirmed as skin malignancies, whereas eight (15%) were benign.

CONCLUSION

With an increasing Internet coverage in Africa, there is potential for smartphone apps to improve health care delivery channels. It is important that mobile apps like NgoziYangu be explored to reduce diagnostic delay and improve the accuracy of detection of skin cancer, especially in stigmatized groups.

摘要

目的

白化病会影响眼睛功能和色素沉着的某些方面,以及头发和皮肤的颜色。据估计,撒哈拉以南非洲地区白化病的患病率为两千至五千人中的一人,而在坦桑尼亚为二百七十人中的一人。坦桑尼亚患有白化病的人面临社会文化和经济差异。由于与白化病相关的污名,他们往往带着包括皮肤癌在内的晚期疾病前往医院就诊。移动健康(mHealth)有助于弥合影响这一人群的皮肤癌检测和治疗方面的一些差距。

方法

我们评估了使用移动应用程序(app)检测白化病患者皮肤癌的可行性。该研究获得了海洋路癌症研究所机构审查委员会的批准。使用移动智能手机收集包括病变图片在内的数据,并提交给专家评审员。专家评审员的诊断选项为良性、恶性或无法评估。

结果

NgoziYangu移动应用程序共捕捉到69名参与者不同身体部位的77个病变。通过该应用程序,62个病变(81%)被判定为恶性,并被转诊进行活检和组织学诊断。在那些被转诊的病变中,55个病变(89%)进行了活检,47个病变(85%)被确诊为皮肤恶性肿瘤,而8个(15%)为良性。

结论

随着非洲互联网覆盖率的不断提高,智能手机应用程序有潜力改善医疗保健服务渠道。探索像NgoziYangu这样的移动应用程序对于减少诊断延误和提高皮肤癌检测的准确性非常重要,尤其是在受污名化的群体中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9033/7531610/35163d87c4de/GO.20.00264f1.jpg

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