Bernstein H G, Kirschke H, Wiederanders B, Kloss P, Rinne A, Dorn A
Institute of Anatomy, Medical Academy Magdeburg, DDR.
J Hirnforsch. 1988;29(1):17-9.
The cellular localization and regional distribution of cathepsin B within rat CNS was revealed by immunohistochemistry using a monospecific antiserum. Cathepsin B protein was found to be widely but unevenly distributed throughout rat brain. Neurons were always cathepsin B immunoreactive. Glial elements were only occasionally immunostained. The distribution of the enzyme resembles largely that of cathepsin D.
利用单特异性抗血清通过免疫组织化学方法揭示了大鼠中枢神经系统中组织蛋白酶B的细胞定位和区域分布。发现组织蛋白酶B蛋白在大鼠脑中广泛但不均匀地分布。神经元始终具有组织蛋白酶B免疫反应性。神经胶质成分仅偶尔被免疫染色。该酶的分布在很大程度上类似于组织蛋白酶D的分布。
