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一种累及额顶部头皮的额部纤维性秃发的新型非典型表现。

A Novel Atypical Presentation of Frontal Fibrosing Alopecia Involving the Frontoparietal Scalp.

作者信息

Goldman Chloe, Diaz Aisleen, Miteva Mariya

机构信息

Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami L. Miller School of Medicine, Miami, Florida, USA.

Department of Dermatology, Ponce Health Sciences University School of Medicine, Ponce, Puerto Rico, USA.

出版信息

Skin Appendage Disord. 2020 Jul;6(4):250-253. doi: 10.1159/000508388. Epub 2020 Jun 12.

Abstract

Frontal fibrosing alopecia (FFA) is a progressive scarring alopecia of unknown etiology that classically presents with a band of hair loss along the frontotemporal scalp. We report a case of FFA involving a band of alopecia along the frontotemporal scalp extending into 2 symmetrical triangles along the parietal scalp reminiscent of the Greek letter upsilon (υ). Trichoscopy demonstrated loss of follicular ostia and peripilar casts. Histology demonstrated altered follicular architecture with decreased follicular density and focal perifollicular fibrosis with a lichenoid infiltrate. Both the trichoscopy and histology support a diagnosis of FFA.

摘要

额部纤维性秃发(FFA)是一种病因不明的进行性瘢痕性秃发,典型表现为额颞部头皮出现一条脱发带。我们报告一例FFA病例,其额颞部头皮的脱发带沿顶叶头皮延伸为两个对称的三角形,形似希腊字母υ(Upsilon)。毛囊镜检查显示毛囊口缺失和毛周角质栓。组织学检查显示毛囊结构改变,毛囊密度降低,局灶性毛囊周围纤维化伴苔藓样浸润。毛囊镜检查和组织学检查均支持FFA的诊断。

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本文引用的文献

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Frontal fibrosing alopecia: An update on the hypothesis of pathogenesis and treatment.额部纤维性秃发:发病机制与治疗假说的最新进展
Int J Womens Dermatol. 2019 Jan 23;5(2):116-123. doi: 10.1016/j.ijwd.2018.11.003. eCollection 2019 Jun.
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Frontal fibrosing alopecia: clinical and prognostic classification.额部纤维性脱发:临床和预后分类。
J Eur Acad Dermatol Venereol. 2017 Oct;31(10):1739-1745. doi: 10.1111/jdv.14287. Epub 2017 May 15.
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Images in clinical medicine. A receding hairline.
N Engl J Med. 2013 Jul 11;369(2):e2. doi: 10.1056/NEJMicm1206227.

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