溃疡性结肠炎中的坏死性肺结节：并非仅是“克罗恩病样”现象
Necrobiotic Pulmonary Nodules in Ulcerative Colitis: Not Just a "Crohnic" Phenomenon.
作者信息
Mukherjee Samiran, Harne Prateek, Mirchia Kanish, Sharma Anuj, Manocha Divey
机构信息
Department of Internal Medicine, SUNY Upstate Medical University, Syracuse, NY.
Department of Pathology, SUNY Upstate Medical University, Syracuse, NY.
出版信息
ACG Case Rep J. 2020 Aug 20;7(8):e00438. doi: 10.14309/crj.0000000000000438. eCollection 2020 Aug.
Necrobiotic pulmonary nodules are an exceptionally rare extraintestinal manifestation of inflammatory bowel disease. Recognition is imperative because it may mimic other autoimmune pathologies such as granulomatosis with polyangiitis or sarcoidosis. We describe a 19-year-old man with a known history of ulcerative colitis who was found to possess bilateral pulmonary nodules on computed tomography imaging. Investigations that included an extensive autoimmune and infectious workup were inconclusive. Biopsy of the nodules revealed fibrinous exudate and palisading histiocytes that confirmed the diagnosis. He was started on prednisone therapy. A follow-up computed tomography a month later revealed near complete resolution.
坏死性肺结节是炎症性肠病一种极其罕见的肠外表现。必须认识到这一点，因为它可能会模仿其他自身免疫性疾病，如肉芽肿性多血管炎或结节病。我们描述了一名19岁有溃疡性结肠炎病史的男性，其在计算机断层扫描成像中发现有双侧肺结节。包括广泛的自身免疫和感染检查在内的各项检查均无定论。结节活检显示有纤维蛋白渗出物和栅栏状组织细胞，从而确诊。他开始接受泼尼松治疗。一个月后的随访计算机断层扫描显示几乎完全消退。
Zotero 插件