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溃疡性结肠炎一种罕见的肠外表现:肺部坏死性结节

An Infrequent Extraintestinal Manifestation of Ulcerative Colitis: Pulmonary Necrobiotic Nodules.

作者信息

Myer Adam S, Shah Kushang, Patel Kinner M

机构信息

Internal Medicine, Stony Brook University, State University of New York, Stony Brook, USA.

Internal Medicine, Stony Brook Medicine University Hospital, Stony Brook, USA.

出版信息

Cureus. 2020 Aug 16;12(8):e9774. doi: 10.7759/cureus.9774.

DOI:10.7759/cureus.9774
PMID:32953292
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7491691/
Abstract

Pulmonary necrobiotic nodules are a rare extraintestinal manifestation (EIM) of inflammatory bowel disease (IBD), which are often overlooked when diagnosing cavitary pulmonary nodules. We present this case to highlight the importance of a thorough differential diagnosis, which includes EIMs of ulcerative colitis (UC), in this case as necrobiotic nodules. Herein, we present a 25-year-old male patient with a history of poorly controlled UC who presented with fevers, left-sided abdominal pain, and bloody diarrhea. Imaging revealed cavitary pulmonary nodules without an infectious or malignant etiology. Lung biopsy and pathology confirmed a diagnosis consistent with necrobiotic nodules.

摘要

肺坏死结节是炎症性肠病(IBD)一种罕见的肠外表现(EIM),在诊断空洞性肺结节时常常被忽视。我们展示这个病例以强调全面鉴别诊断的重要性,其中包括溃疡性结肠炎(UC)的肠外表现,在本病例中即坏死结节。在此,我们报告一名25岁男性患者,有溃疡性结肠炎控制不佳病史,出现发热、左侧腹痛和血性腹泻。影像学检查发现有空洞性肺结节,无感染或恶性病因。肺活检及病理检查确诊为符合坏死结节的诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad51/7491691/3504d931cfd1/cureus-0012-00000009774-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad51/7491691/f851a41c9883/cureus-0012-00000009774-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad51/7491691/814b50b47f89/cureus-0012-00000009774-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad51/7491691/3504d931cfd1/cureus-0012-00000009774-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad51/7491691/f851a41c9883/cureus-0012-00000009774-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad51/7491691/814b50b47f89/cureus-0012-00000009774-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad51/7491691/3504d931cfd1/cureus-0012-00000009774-i03.jpg

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本文引用的文献

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Mesalazine-related lung disease in a patient with ulcerative colitis: A case report.一名溃疡性结肠炎患者的美沙拉嗪相关肺部疾病:病例报告
Medicine (Baltimore). 2018 Nov;97(48):e13242. doi: 10.1097/MD.0000000000013242.
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Gastroenterol Res Pract. 2018 Aug 12;2018:5697846. doi: 10.1155/2018/5697846. eCollection 2018.
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