Kono Taro, Chan Henry H L, Groff William F, Imagawa Kotaro, Hanai Ushio, Akamatsu Tadashi
Department of Plastic Surgery, Tokai University, Kanagawa, Japan.
Division of Dermatology, Department of Medicine, University of Hong Kong, Department of Medicine/Therapeutic and Pediatric, Chinese University of Hong Kong.
Laser Ther. 2020 Jul 17;29(1):47-52. doi: 10.5978/islsm.20-OR-07.
Although, the pulse width should be shorter than the thermal relaxation time of the target, nanosecond laser pulses are not short enough for tattoo removal. Complications are common, such as hyper or hypopigmentation, textural changes, and scarring. Moreover, patients with darker skin types are at a higher risk of complications from tattoo removal using these lasers. Picosecond lasers were developed to overcome the limitation of nanosecond lasers. We did a comparison study of a 532/1064 nm picosecond laser vs a 532/1064 nm nanosecond laser to evaluate the clinical efficacy and complications of multi-color tattoos in Asians.
Eleven Asian patients with 37 professional tattoos were enrolled in the study. Each patient was treated with a 532/1064 nm nanosecond laser and a 532/1064 nm picosecond laser. The spot size that was used with each laser was 3 mm. Four treatments were performed, with four week intervals between each treatment. Patients were examined a week after the first treatment and 3 months after the last treatment.
All patients tolerated the treatments well. The efficacy of the 1064 nm picosecond laser for black tattoos is significantly better than the other studied lasers. The efficacy of the 532 nm picosecond laser is significantly better than the other studied lasers for red tattoos. The efficacy of the 532 nm picosecond laser is significantly better than the 532 nm nanosecond laser and better than the 1064 nm picosecond laser for green tattoos. Mild to moderate post-inflammatory hyperpigmentation was observed in 35.1%, 24.3% 27.0%, and 21.6% of the tattoos treated with the 532 nm nanosecond laser, the 532 nm picosecond laser, the 1064 nm nanosecond laser, and the 1064 nm pico-second laser, respectively. Paradoxical darkening (5.4%) was observed equally with each type of laser. There was no scar formation in any of the tattoos treated. The 532/1064 nm picosecond laser is more effective than the 532/1064 nm nanosecond laser in the treatment of multi-color tattoos in Asians. The 532 nm picosecond laser is more effective than 1064 nm picosecond laser in every tattoo color, with the exception of black. Paradoxical darkening was observed, even the use of picosecond lasers.
尽管脉冲宽度应短于目标组织的热弛豫时间，但纳秒激光脉冲对于纹身去除来说仍不够短。并发症很常见，如色素沉着过度或不足、质地改变和瘢痕形成。此外，皮肤颜色较深的患者使用这些激光进行纹身去除时发生并发症的风险更高。皮秒激光的开发是为了克服纳秒激光的局限性。我们进行了一项532/1064纳米皮秒激光与532/1064纳米纳秒激光的对比研究，以评估亚洲人多色纹身的临床疗效和并发症。
11名患有37处专业纹身的亚洲患者参与了该研究。每位患者均接受532/1064纳米纳秒激光和532/1064纳米皮秒激光治疗。每种激光使用的光斑尺寸均为3毫米。共进行了4次治疗，每次治疗间隔4周。在首次治疗后1周和最后一次治疗后3个月对患者进行检查。
所有患者对治疗的耐受性良好。1064纳米皮秒激光对黑色纹身的疗效明显优于其他研究的激光。532纳米皮秒激光对红色纹身的疗效明显优于其他研究的激光。532纳米皮秒激光对绿色纹身的疗效明显优于532纳米纳秒激光且优于1064纳米皮秒激光。分别用532纳米纳秒激光、532纳米皮秒激光、1064纳米纳秒激光和1064纳米皮秒激光治疗的纹身中，有35.1%、24.3%、27.0%和21.6%出现了轻至中度的炎症后色素沉着。每种激光均观察到同等比例（5.4%）的反常变黑现象。所有治疗的纹身均未形成瘢痕。532/1064纳米皮秒激光在治疗亚洲人的多色纹身方面比532/1064纳米纳秒激光更有效。除黑色纹身外，532纳米皮秒激光在每种纹身颜色的治疗上均比1064纳米皮秒激光更有效。即使使用皮秒激光也观察到了反常变黑现象。
