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苏丹喀土穆放射与同位素中心的乳腺癌五年生存率。

The five-year survival rate of breast cancer at Radiation and Isotopes Centre Khartoum, Sudan.

作者信息

Abdalla Elhassan Samah Isam

机构信息

Faculty of Medicine, University of Khartoum, ElQasr Avenue, 11111, Khartoum, Sudan.

出版信息

Heliyon. 2020 Aug 20;6(8):e04615. doi: 10.1016/j.heliyon.2020.e04615. eCollection 2020 Aug.

Abstract

BACKGROUND

The Radiation and Isotopes Centre Khartoum (RICK) is the largest public cancer centre in Sudan. The most common cancer in Sudan (and RICK) is breast cancer. The study aims to determine the five year survival of breast cancer as well as factors influencing this survivorship.

METHODS

This retrospective facility-based study was conducted on patients diagnosed as having breast cancer at RICK during the year 2013. At 305 patients, the population under study was totally covered. Data analysis was conducted using SPSS version 23. Kaplan-Meier method was used to estimate survival, and to further plot it against specific variables.

RESULTS

The five-year survival was found to be 79%. Lymph nodes were involved in 70.5% of the cases. The mean time between patients' first discovery of symptoms and diagnosis at RICK was 13.03 months. Presence of comorbid diabetes and hypertension significantly increased breast cancer mortality.

CONCLUSIONS

Breast cancer in Sudan is characterized by younger age, delayed diagnosis and advanced staging at presentation, as well as lower five-year breast cancer survival in comparison to developed countries.

摘要

背景

喀土穆辐射与同位素中心(RICK)是苏丹最大的公立癌症中心。苏丹(以及RICK)最常见的癌症是乳腺癌。本研究旨在确定乳腺癌的五年生存率以及影响该生存率的因素。

方法

这项基于机构的回顾性研究针对2013年在RICK被诊断为患有乳腺癌的患者开展。共纳入305例患者,涵盖了所有研究对象。使用SPSS 23版进行数据分析。采用Kaplan-Meier方法估计生存率,并进一步针对特定变量绘制生存曲线。

结果

发现五年生存率为79%。70.5%的病例有淋巴结受累。患者首次发现症状到在RICK确诊的平均时间为13.03个月。合并糖尿病和高血压显著增加乳腺癌死亡率。

结论

苏丹的乳腺癌具有发病年龄较轻、诊断延迟、就诊时分期较晚的特点,并且与发达国家相比,五年乳腺癌生存率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/994f/7452576/19140e4b8ebc/gr1.jpg

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