Desalegn Defaru, Girma Shimelis, Tessema Worknesh, Yeshigeta Eyerusalem, Kebeta Teshome
Department of Psychiatry, College of Health Science, Mettu University, Mettu, Ethiopia.
Department of Psychiatry, Institute of Health, Jimma University, Jimma, Ethiopia.
Psychiatry J. 2020 Aug 21;2020:4065082. doi: 10.1155/2020/4065082. eCollection 2020.
Schizophrenia is one of the most severe, chronic, and disabling mental disorders found globally. The chronic nature of the illness significantly interferes with functioning and results in a poor quality of life, but little is known about the quality of life among schizophrenia patients, in particular in low-income countries. Therefore, we assessed the quality of life and associated factors among patients with schizophrenia attending Jimma University Medical Center, Southwest Ethiopia.
The hospital-based cross-sectional study design was employed to collect data from 352 study participants using a systematic random sampling technique from June to July 2018. Patients' sociodemographic characteristic, quality of life, psychopathology, medication adherence, comorbid physical illness, and substance use disorder were assessed. Data entry and analysis were done using EpiData version 3.1 and Statistical Package for the Social Sciences (SPSS) version 21.0, respectively. Variables with a value < 0.05 in the final multiple regression models were declared to be associated with the outcome variable. . The response rate of the study was 99.7%. The mean (±standard deviation) score of the World Health Organization Quality of Life Assessment Short Version Scale was 74.34 ± 15.83. Positive symptoms, negative symptoms, general psychopathologies, comorbid physical illness, khat use disorder, tobacco use disorder, and medication nonadherence were negatively associated with patient quality of life. However, monthly income was found to be positively associated with quality of life. . The mean and standard deviation of the quality of life of people with schizophrenia is found to be 74.34 ± 15.83 in this study. The social relationship domain was found with the lowest mean score. Therefore, priority interventions need to be implemented to improve the social deficits.
精神分裂症是全球发现的最严重、慢性且致残的精神障碍之一。该疾病的慢性性质严重干扰了功能，并导致生活质量低下，但对于精神分裂症患者的生活质量，尤其是低收入国家患者的生活质量，人们了解甚少。因此，我们评估了埃塞俄比亚西南部吉马大学医学中心精神分裂症患者的生活质量及相关因素。
采用基于医院的横断面研究设计，于2018年6月至7月使用系统随机抽样技术从352名研究参与者中收集数据。评估了患者的社会人口学特征、生活质量、精神病理学、药物依从性、合并躯体疾病和物质使用障碍。分别使用EpiData 3.1版和社会科学统计软件包（SPSS）21.0版进行数据录入和分析。在最终的多元回归模型中，P值<0.05的变量被宣布与结果变量相关。该研究的应答率为99.7%。世界卫生组织生活质量评估简表的平均（±标准差）得分为74.34±15.83。阳性症状、阴性症状、一般精神病理学、合并躯体疾病、恰特草使用障碍、烟草使用障碍和药物不依从与患者生活质量呈负相关。然而，发现月收入与生活质量呈正相关。在本研究中，精神分裂症患者生活质量的均值和标准差为74.34±15.83。发现社会关系领域的平均得分最低。因此，需要实施优先干预措施以改善社会缺陷。
