Hao Xiaopei, Dai Kunfu, He Yuting, Tao Lianyuan, Yu Haibo
Department of Hepatobiliary Surgery, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou, China.
Wideochir Inne Tech Maloinwazyjne. 2020 Sep;15(3):462-468. doi: 10.5114/wiitm.2019.89655. Epub 2019 Nov 11.
The safety and feasibility of laparoscopic splenectomy plus selective esophagogastric devascularization (LSSD) via the spleen bed for cirrhotic portal hypertension have not been well studied.
To assess the safety and feasibility of LSSD via the spleen bed for patients with cirrhotic portal hypertension.
From June 2012 to December 2017, 423 patients suffering from portal hypertension and hypersplenism with liver cirrhosis underwent surgery in our department. One hundred and sixty-seven of these patients received totally LSSD, and the others received open splenectomy and esophagogastric devascularization (OSD). The characteristics, intraoperative and postoperative details and complications of the two groups were compared.
The operations were successfully performed in all patients. Intraoperative blood loss volume and blood transfusion were similar between the two groups (all p-values > 0.05). Postoperative length of hospital stay and time to oral intake were significantly shorter, but operation time was longer in the LSSD group compared with the OSD group (all p < 0.05). However, postoperative portal vein diameter was significantly smaller in the LSSD group (p < 0.001). The postoperative grade of varices was significantly lower in the LSSD group (p = 0.030). No significant differences were detected between the two groups regarding postoperative liver function, but the incidences of pancreatic leakage, pleural effusion, and wound infections were higher in the OSD group (all p < 0.05).
LSSD via the spleen bed is safe and feasible for liver cirrhosis and portal hypertension.
经脾床行腹腔镜脾切除术加选择性食管胃去血管化术(LSSD)治疗肝硬化门静脉高压症的安全性和可行性尚未得到充分研究。
评估经脾床行LSSD治疗肝硬化门静脉高压症患者的安全性和可行性。
2012年6月至2017年12月,我科对423例肝硬化门静脉高压症合并脾功能亢进患者进行了手术。其中167例患者接受了完全LSSD,其余患者接受了开腹脾切除术和食管胃去血管化术(OSD)。比较两组患者的特征、术中及术后详细情况和并发症。
所有患者手术均成功完成。两组术中失血量和输血量相似(所有p值>0.05)。与OSD组相比,LSSD组术后住院时间和开始经口进食时间明显缩短,但手术时间较长(所有p<0.05)。然而,LSSD组术后门静脉直径明显较小(p<0.001)。LSSD组术后静脉曲张分级明显较低(p=0.030)。两组术后肝功能无明显差异,但OSD组胰漏、胸腔积液和伤口感染发生率较高(所有p<0.05)。
经脾床行LSSD治疗肝硬化和门静脉高压症是安全可行的。