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微粒皮移植治疗大面积烧伤:初步报告。

Microskin grafting in the treatment of extensive burns: a preliminary report.

作者信息

Zhang M L, Chang Z D, Wang C Y, Fang C H

机构信息

Department of Burns, Beijing Jishuitan Hospital, China.

出版信息

J Trauma. 1988 Jun;28(6):804-7.

PMID:3290505
Abstract

Microskin grafting has proved to be an effective new procedure for the treatment of extensive burns, in which only a minimum amount of autogenous skin is needed for coverage of a large full-thickness burn wound. The technique has been improved and applied in 17 major burn patients. All patients survived. The wound covered with microskin grafts ranged from 6% to 45% TBSA, with a mean area of 24.1% TBSA. The expansion ratio of micrografts in this series reached up to 1:18, and can be greater. The wound healing was accomplished in three ways. 1) Wounds were completely resurfaced by micrografts in 24 limbs (58.5%). 2) Wounds were not totally healed with micrografts by the time the homograft was rejected, leaving only small raw areas which needed re-grafting in 12 limbs (29.3%). 3) The micrografts did not take on four limbs and one chest wall (12.2%). The improved technique, which has become more simple and feasible, is discussed in detail.

摘要

微粒皮移植已被证明是治疗大面积烧伤的一种有效的新方法,对于大面积全层烧伤创面的覆盖,仅需少量自体皮肤。该技术已得到改进并应用于17例重度烧伤患者。所有患者均存活。微粒皮移植覆盖的创面面积占总体表面积(TBSA)的6%至45%,平均面积为24.1%TBSA。本系列中微粒皮的扩增比例高达1:18,且可能更高。创面通过三种方式愈合。1)24条肢体(58.5%)的创面完全被微粒皮覆盖。2)在同种异体皮被排斥时,微粒皮未能完全愈合创面,12条肢体(29.3%)仅留下小面积的创面需要再次移植。3)4条肢体和1个胸壁(12.2%)的微粒皮未存活。本文详细讨论了已变得更加简单可行的改良技术。

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1
Microskin grafting in the treatment of extensive burns: a preliminary report.微粒皮移植治疗大面积烧伤:初步报告。
J Trauma. 1988 Jun;28(6):804-7.
2
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引用本文的文献

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Effect of the orientation of microskin on the survival rate of transplantation and improving the method.微小皮片方向对移植成活率的影响及改进方法
Int J Clin Exp Pathol. 2021 Feb 1;14(2):186-195. eCollection 2021.
2
Skin tissue engineering advances in severe burns: review and therapeutic applications.严重烧伤的皮肤组织工程学进展:综述与治疗应用。
Burns Trauma. 2016 Feb 19;4:3. doi: 10.1186/s41038-016-0027-y. eCollection 2016.
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History of burns: The past, present and the future.烧伤史:过去、现在和未来。
Burns Trauma. 2014 Oct 25;2(4):169-80. doi: 10.4103/2321-3868.143620. eCollection 2014.
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Sandwich-type fiber scaffolds with square arrayed microwells and nanostructured cues as microskin grafts for skin regeneration.作为用于皮肤再生的微皮移植物的具有方阵阵列微凹坑和纳米结构线索的夹层型纤维支架。
Biomaterials. 2014 Jan;35(2):630-41. doi: 10.1016/j.biomaterials.2013.09.111. Epub 2013 Oct 18.
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Unusual donor sites for harvesting of island skin grafts.用于获取岛状皮瓣的不寻常供区。
Ann Burns Fire Disasters. 2008 Dec 31;21(4):206-9.
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Co-graft of acellular dermal matrix and autogenous microskin in a child with extensive burns.脱细胞真皮基质与自体微粒皮联合移植治疗儿童大面积烧伤
Ann Burns Fire Disasters. 2008 Jun 30;21(2):102-6.
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Successful treatment of a patient with an extraordinarily large deep burn.成功治疗一名深度特大烧伤患者。
Med Sci Monit. 2011 Apr;17(4):CS47-51. doi: 10.12659/msm.881704.
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The micrograft concept for wound healing: strategies and applications.伤口愈合的微移植概念:策略与应用
J Diabetes Sci Technol. 2010 Jul 1;4(4):808-19. doi: 10.1177/193229681000400407.
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[Early surgical management of severe burns].[严重烧伤的早期手术治疗]
Unfallchirurg. 2006 Apr;109(4):270-7. doi: 10.1007/s00113-006-1073-x.