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本文引用的文献

1
Cancer-treatment-induced neurotoxicity--focus on newer treatments.癌症治疗引起的神经毒性——聚焦于新型治疗方法。
Nat Rev Clin Oncol. 2016 Feb;13(2):92-105. doi: 10.1038/nrclinonc.2015.152. Epub 2015 Sep 22.
2
Association of an inherited genetic variant with vincristine-related peripheral neuropathy in children with acute lymphoblastic leukemia.遗传性遗传变异与儿童急性淋巴细胞白血病 vincristine 相关周围神经病的关联。
JAMA. 2015 Feb 24;313(8):815-23. doi: 10.1001/jama.2015.0894.
3
Chemotherapy-induced peripheral neurotoxicity in the era of pharmacogenomics.药物基因组学时代的化疗诱导性周围神经毒性。
Lancet Oncol. 2011 Nov;12(12):1151-61. doi: 10.1016/S1470-2045(11)70131-0. Epub 2011 Jun 28.
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CNS complications of radiotherapy and chemotherapy.放疗和化疗的中枢神经系统并发症
Lancet. 2009 Nov 7;374(9701):1639-51. doi: 10.1016/S0140-6736(09)61299-X.
5
Central nervous system toxicity from cancer treatment.癌症治疗引起的中枢神经系统毒性。
Curr Oncol Rep. 2004 Jan;6(1):11-9. doi: 10.1007/s11912-996-0004-x.
6
Methylene blue in the treatment and prevention of ifosfamide-induced encephalopathy: report of 12 cases and a review of the literature.亚甲蓝治疗和预防异环磷酰胺所致脑病：12例报告及文献复习
Br J Cancer. 2000 Jan;82(2):291-4. doi: 10.1054/bjoc.1999.0917.

化疗和靶向药物中枢神经系统毒性的管理：2020年

Management of CNS toxicity of chemotherapy and targeted agents: 2020.

作者信息

Cintrón-García Juan, Guddati Achuta Kumar

机构信息

Division of Hematology/Oncology, Georgia Cancer Center, Augusta University Augusta, GA 30909, USA.

出版信息

Am J Cancer Res. 2020 Aug 1;10(8):2617-2620. eCollection 2020.

PMID:32905442
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7471356/
Abstract

Cancer treatment has evolved significantly over the last two decades. With the advent of targeted therapy, immunotherapy and immunotherapeutic agents conjugated to toxins, the spectrum of side effects has increased. This work is a compilation of side effects on the central nervous system due to various chemotherapeutic and immunotherapy agents followed by their recommended management.

摘要

在过去二十年中，癌症治疗有了显著进展。随着靶向治疗、免疫治疗以及与毒素偶联的免疫治疗药物的出现，副作用的范围有所增加。这项工作汇总了各种化疗和免疫治疗药物对中枢神经系统的副作用及其推荐的处理方法。