化疗和靶向药物肾毒性的管理：2020年
Management of nephrotoxicity of chemotherapy and targeted agents: 2020.
作者信息
Chiruvella Varsha, Annamaraju Pavan, Guddati Achuta K
机构信息
Division of Hematology/Oncology, Georgia Cancer Center, Augusta University Augusta, GA 30909, USA.
Department of Medicine, Liberty University College of Medicine Lynchburg, VA, USA.
出版信息
Am J Cancer Res. 2020 Dec 1;10(12):4151-4164. eCollection 2020.
Abstract
Nephrotoxic effects of certain chemotherapeutic agents such as cisplatin and ifosfamide has been well documented and these effects are carefully managed by oncologists during their usage. The introduction of targeted agents has added a new challenge to cancer management as their nephrotoxic effects and associated management is in the process of being adopted by oncologists. This work is a compilation of side effects on the renal system due to various chemotherapeutic, immunotherapeutic and targeted agents followed by their recommended management.
摘要
某些化疗药物（如顺铂和异环磷酰胺）的肾毒性作用已有充分记录，肿瘤学家在使用这些药物时会谨慎处理这些影响。靶向药物的引入给癌症治疗带来了新的挑战，因为它们的肾毒性作用及相关处理方法正处于被肿瘤学家采用的过程中。这项工作汇编了各种化疗药物、免疫治疗药物和靶向药物对肾脏系统的副作用及其推荐的处理方法。
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