Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
Department of Neuropsychiatry, Tottori University Faculty of Medicine, Yonago, Tottori, Japan.
J Am Geriatr Soc. 2021 Jan;69(1):140-147. doi: 10.1111/jgs.16815. Epub 2020 Sep 9.
BACKGROUND/OBJECTIVES: Detecting delirium is important to identify patients with a high risk of poor outcomes. Although many different kinds of screening instruments for delirium exist, there is no solid consensus about which methods are the most effective. In addition, it is important to find the most useful tools in predicting outcomes such as mortality.
Retrospective cohort study.
University of Iowa Hospitals and Clinics.
A total of 1,125 adult inpatients (mean age = 67.7; median age = 69).
Post hoc analyses were performed based on existing data from the Confusion Assessment Method for Intensive Care Unit (CAM-ICU), Delirium Rating Scale-Revised-98 (DRS), and the Delirium Observation Screening Scale (DOSS). Correlation among these scales and relationships between 365-day mortality and each scale were evaluated.
A positive result on the CAM-ICU ("CAM-ICU positive") was associated with higher DRS and DOSS scores. A DRS score = 9/10 was the best cutoff to detect CAM-ICU positive, and DOSS = 2/3 was the best cutoff to detect CAM-ICU positive. CAM-ICU positive was associated with high 365-day mortality. DRS score = 9/10 and DOSS score = 0/1 were found to differentiate mortality risk the most significantly. Higher DRS and DOSS scores significantly coincided with a decrease in a patient's survival rate at 365 days.
The best DRS and DOSS cutoff scores to differentiate 365-day mortality risk were lower than those commonly used to detect delirium in the literature. New cutoff scores for the DRS and DOSS might be useful in differentiating risk of mortality among hospital patients.
背景/目的:识别谵妄对于确定具有不良结局高风险的患者很重要。虽然存在许多不同类型的谵妄筛查工具,但对于哪种方法最有效尚无明确共识。此外,找到最有用的工具来预测死亡率等结果也很重要。
回顾性队列研究。
爱荷华大学医院和诊所。
共有 1125 名成年住院患者(平均年龄=67.7;中位数年龄=69)。
基于重症监护病房意识模糊评估法(CAM-ICU)、修订版谵妄评定量表-98(DRS)和谵妄观察筛查量表(DOSS)的现有数据进行事后分析。评估了这些量表之间的相关性以及与 365 天死亡率的关系。
CAM-ICU 呈阳性(“CAM-ICU 阳性”)与更高的 DRS 和 DOSS 评分相关。DRS 评分为 9/10 是检测 CAM-ICU 阳性的最佳截断值,DOSS=2/3 是检测 CAM-ICU 阳性的最佳截断值。CAM-ICU 阳性与高 365 天死亡率相关。DRS 评分=9/10 和 DOSS 评分=0/1 被发现最能显著区分死亡率风险。DRS 和 DOSS 评分越高,患者在 365 天的生存率越低。
区分 365 天死亡率风险的最佳 DRS 和 DOSS 截断评分低于文献中用于检测谵妄的常用评分。DRS 和 DOSS 的新截断评分可能有助于区分住院患者的死亡风险。