Ceramic Physics Laboratory, Kyoto Institute of Technology, Sakyo-ku, Matsugasaki 606-8585, Kyoto, Japan.
Department of Immunology, Kyoto Prefectural University of Medicine, Kamigyo-ku 602-8566, Kyoto, Japan.
Biomed Mater. 2020 Dec 11;16(1). doi: 10.1088/1748-605X/abb6b1.
Surface roughness, bioactivity, and antibacterial properties are desirable in skeletal implants. We hot-pressed a mix of particulate sodium chloride (NaCl) salt and silicon nitride (β-SiN) onto the surface of bulk PEEK. NaCl grains were removed by leaching in water, resulting in a porous PEEK surface embedded with sim15 vol% β-SiNparticles. This functionalized surface showed the osteogenic and antibacterial properties previously reported in bulk silicon nitride implants. Surface enhancement of PEEK with β-SiNcould improve the performance of spinal fusion cages, by facilitating arthrodesis and resisting bacteria.
在骨骼植入物中，表面粗糙度、生物活性和抗菌性能是理想的。我们将氯化钠（NaCl）颗粒和氮化硅（β-SiN）的混合物热压到大块聚醚醚酮（PEEK）的表面上。通过在水中浸出，NaCl 颗粒被去除，从而在嵌入有 sim15 体积%β-SiN 颗粒的多孔 PEEK 表面上形成。这种功能化表面表现出以前在块状氮化硅植入物中报道的成骨和抗菌性能。用β-SiN 增强 PEEK 的表面性能可以通过促进融合和抵抗细菌来提高脊柱融合笼的性能。
