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[测定肾脏个体清除率的方法选择]

[Choice of method for determining the individual clearance of the kidneys].

作者信息

Narkevich B Ia, Kashkadaeva A V, Sorokin A I, Averinova S G

出版信息

Med Radiol (Mosk). 1988 Jun;33(6):82-6.

PMID:3290612
Abstract

Some criteria for assessment of the adequacy of various radionuclide methods of determination of the separate renal clearance were proposed. Some methods were analyzed according to these criteria: one of them was proposed by S. U. Schlegel et al. and used in the paper by M. E. Karaev and R. N. Samedov, and the other one was proposed by V. Kh. Frenkel' and V. B. Shushkovskiĭ. Both methods were shown to be insufficiently substantiated from physiological and mathematical view-points. A method of assessment of the separate renal clearance in the form of a circulation model was proposed. It was based on the minimal possible number of simplifying allowances and made it possible to define the state of secretory-excretory (or filtration) function and the state of hemodynamics of each kidney as a result of single administration of a transit nephrotropic radiopharmaceutical.

摘要

提出了评估各种放射性核素方法测定单独肾清除率是否充分的一些标准。根据这些标准对一些方法进行了分析:其中一种方法由S. U. 施莱格尔等人提出,并被M. E. 卡拉耶夫和R. N. 萨梅多夫在论文中使用,另一种方法由V. Kh. 弗伦克尔和V. B. 舒什科夫斯基提出。从生理学和数学观点来看,这两种方法都没有得到充分的论证。提出了一种以循环模型形式评估单独肾清除率的方法。它基于尽可能少的简化假设,并且通过单次给予一种经肾转运放射性药物,有可能确定每个肾脏的分泌 - 排泄(或滤过)功能状态和血流动力学状态。

相似文献

1
[Choice of method for determining the individual clearance of the kidneys].[测定肾脏个体清除率的方法选择]
Med Radiol (Mosk). 1988 Jun;33(6):82-6.
2
[Further comment on the individual function of the kidneys (apropos the article by M. E. Karaev and R. N. Samedov, "Determination of effective renal plasma flow based on data from dynamic renoscintigraphy with 131I-hippuran"].[关于肾脏个体功能的进一步评论(关于M. E. 卡拉耶夫和R. N. 萨梅多夫的文章《基于131I-马尿酸动态肾闪烁显像数据测定有效肾血浆流量》)]
Med Radiol (Mosk). 1988 Jun;33(6):78-82.
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[Comparison of simple nuclear medical methods of determining renal clearance].[用于测定肾脏清除率的简单核医学方法比较]
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Absorbed radiation dose in adults from iodine-131 and iodine-123 orthoiodohippurate and technetium-99m DTPA renography.
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