Cooper Emily, Jones Leah, Joseph Annie, Allison Rosie, Gold Natalie, Larcombe James, Moore Philippa, McNulty Cliodna A M
Primary Care and Interventions Unit, Public Health England, Twyver House, Bruton Way, Gloucester GL1 1DQ, UK.
Nottingham University Hospitals, Hucknall Rd, Nottingham NG5 1PB, UK.
Antibiotics (Basel). 2020 Sep 7;9(9):581. doi: 10.3390/antibiotics9090581.
To inform interventions to improve antimicrobial use in urinary tract infections (UTIs) and contribute to a reduction in bloodstream infection, we explored factors influencing the diagnosis and management of UTIs in primary care. Semi-structured focus groups informed by the Theoretical Domains Framework. General practice (GP) surgeries in two English clinical commissioning groups (CCGs), June 2017 to March 2018. A total of 57 GP staff within 8 focus groups. Staff were very aware of common UTI symptoms and nitrofurantoin as first-line treatment, but some were less aware about when to send a urine culture, second-line and non-antibiotic management, and did not probe for signs and symptoms to specifically exclude vaginal causes or pyelonephritis before prescribing. Many consultations were undertaken over the phone, many by nurse practitioners, and followed established protocols that often included urine dipsticks and receptionists. Patient expectations increased use of urine dipsticks, and immediate and 5 days courses of antibiotics. Management decisions were also influenced by patient co-morbidities. No participants had undertaken recent UTI audits. Patient discussions around antibiotic resistance and back-up antibiotics were uncommon compared to consultations for respiratory infections. Knowledge and skill gaps could be addressed with education and clear, accessible, UTI diagnostic and management guidance and protocols that are also appropriate for phone consultations. Public antibiotic campaigns and patient-facing information should cover UTIs, non-pharmaceutical recommendations for "self-care", prevention and rationale for 3 days antibiotic courses. Practices should be encouraged to audit UTI management.
为了为改善尿路感染(UTIs)中抗菌药物使用的干预措施提供信息,并有助于减少血流感染,我们探讨了基层医疗中影响UTIs诊断和管理的因素。基于理论领域框架开展了半结构化焦点小组讨论。2017年6月至2018年3月期间,在英国两个临床委托小组(CCGs)的全科医疗(GP)诊所进行。8个焦点小组中共有57名GP工作人员。工作人员非常了解常见的UTI症状以及将呋喃妥因作为一线治疗药物,但有些人对何时送检尿培养、二线治疗和非抗生素管理了解较少,并且在开处方前没有询问体征和症状以专门排除阴道病因或肾盂肾炎。许多咨询是通过电话进行的,许多是由执业护士进行的,并且遵循了通常包括尿试纸和接待员的既定规程。患者的期望增加了尿试纸的使用以及立即和5天疗程的抗生素使用。管理决策也受到患者合并症的影响。没有参与者进行过近期的UTI审核。与呼吸道感染咨询相比,围绕抗生素耐药性和备用抗生素的患者讨论并不常见。知识和技能差距可以通过教育以及清晰、易懂、适用于电话咨询的UTI诊断和管理指南及规程来解决。公共抗生素宣传活动和面向患者的信息应涵盖UTIs、“自我护理”的非药物建议、预防措施以及3天抗生素疗程的理由。应鼓励医疗机构审核UTI管理情况。