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聚合物凝胶与生物组织的纳米力学:对赫兹区域及以外分析方法的批判性综述。

Nanomechanics of polymer gels and biological tissues: A critical review of analytical approaches in the Hertzian regime and beyond.

作者信息

Lin David C, Horkay Ferenc

机构信息

Laboratory of Integrative and Medical Biophysics, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Soft Matter. 2008 Mar 20;4(4):669-682. doi: 10.1039/b714637j.

DOI:10.1039/b714637j
PMID:32907170
Abstract

We survey recent progress in the application of nanoindentation to characterize the local mechanical properties of polymer gels and biological tissues. We review the theories, analytical models based thereon, and data processing techniques commonly used to determine elastic properties of these classes of materials by instrumented nanoindentation. Examples from the testing of synthetic and biological gels are used to illustrate the limitations of existing theories and approaches. Emphasis is placed on the need for contact mechanics models that more accurately represent the large-strain behaviour of soft matter.

摘要

我们综述了纳米压痕技术在表征聚合物凝胶和生物组织局部力学性能方面的最新进展。我们回顾了用于通过仪器化纳米压痕测定这些材料类别的弹性性能的理论、基于这些理论的分析模型以及常用的数据处理技术。通过合成凝胶和生物凝胶测试的实例来说明现有理论和方法的局限性。重点强调了需要更准确地描述软物质大应变行为的接触力学模型。

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