Htet Zaw Win, Tai E Shyong, Yang Samantha Peiling
Division of Endocrinology, Department of Medicine, National University Hospital, Level 10, NUHS Tower Block, 1E Kent Ridge Road, Singapore 119228.
Division of Endocrinology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Level 10, NUHS Tower Block, 1E Kent Ridge Road, Singapore 119228.
Case Rep Endocrinol. 2020 Aug 25;2020:7104806. doi: 10.1155/2020/7104806. eCollection 2020.
Fine needle aspiration (FNA) of thyroid nodules is a simple, reliable, and inexpensive procedure performed on suspicious thyroid nodules found in thyroid ultrasound (US). Acute bacterial suppurative thyroiditis is an uncommon complication of FNA which, however, can be life threatening. . A 49-year-old lady presented with fever and neck pain 1 month after FNA with biochemical evidence of thyrotoxicosis. Repeat US of the thyroid showed interval enlargement of the thyroid nodule, and the culture of the cystic fluid of repeat FNA grew . She responded well to bedside aspiration and 2 weeks of antibiotic therapy without requiring surgical intervention. . Acute bacterial suppurative thyroiditis following FNA has been increasingly reported in immunocompetent hosts. There are 2 peculiar features in our case: a smoldering course caused by an indolent organism and a significant time lag between initial FNA and clinical presentation. On literature review, it was found that the onset of acute bacterial suppurative thyroiditis after FNA can range from a few days to up to 3 months. Clinicians should be aware of this complication even if FNA has been performed a few months ago. Thyroid US and US-guided FNA are useful initial investigations. Conventional management of acute bacterial suppurative thyroiditis has been surgery combined with antimicrobial therapy. However, recently, a more conservative approach has been reported to be effective in the treatment of acute bacterial suppurative thyroiditis as well.
Proper infection control practices are necessary in performing the FNA. Initial management (conservative versus surgical) of acute bacterial thyroiditis should be based on the patient's clinical status and the extent of infective focus.
甲状腺结节细针穿刺抽吸术(FNA)是一种针对甲状腺超声(US)检查发现的可疑甲状腺结节所进行的简单、可靠且费用低廉的操作。急性细菌性化脓性甲状腺炎是FNA一种罕见但可能危及生命的并发症。一名49岁女性在FNA术后1个月出现发热和颈部疼痛,并有甲状腺毒症的生化证据。甲状腺的重复超声检查显示甲状腺结节进行性增大,重复FNA的囊液培养生长出……她经床旁抽吸和2周抗生素治疗后反应良好,无需手术干预。免疫功能正常的宿主中,FNA后发生急性细菌性化脓性甲状腺炎的报道日益增多。我们的病例有两个特殊之处:由一种生长缓慢的病原体引起的隐匿病程,以及初次FNA与临床表现之间存在显著的时间间隔。经文献检索发现,FNA后急性细菌性化脓性甲状腺炎的发病时间可从几天到3个月不等。即使FNA是在几个月前进行的,临床医生也应意识到这种并发症。甲状腺超声和超声引导下FNA是有用的初步检查手段。急性细菌性化脓性甲状腺炎的传统治疗方法是手术联合抗菌治疗。然而,最近有报道称,一种更保守的方法在治疗急性细菌性化脓性甲状腺炎方面也有效。
进行FNA时必须采取适当的感染控制措施。急性细菌性甲状腺炎的初始治疗(保守治疗还是手术治疗)应基于患者的临床状况和感染灶的范围。