男男性行为者 HIV 感染者居家采集干血斑标本进行纵向病毒载量监测：一项可行性试点研究结果。
Longitudinal Viral Load Monitoring Using Home-Collected Dried Blood Spot Specimens of MSM Living with HIV: Results from a Feasibility Pilot Study.
机构信息
Department of Epidemiology, Columbia University Mailman School of Public Health, 722 West 168th Street, 7th Floor, New York, NY, 10032, USA.
Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
出版信息
AIDS Behav. 2021 Mar;25(3):661-666. doi: 10.1007/s10461-020-03030-w.
Novel viral load monitoring strategies are needed to help individuals maintain an undetectable viral load (UVL). In 2018, U.S. MSM living with HIV with a past detectable VL received a dried blood spot (DBS) kit at baseline and 3-month follow-up and returned specimens to a research laboratory. Of 56 consenting participants, 91% returned specimens at baseline and 77% at 3-month follow-up; 74% who returned two specimens had UVL at both time points. At-home DBS collection and longitudinal VL monitoring is feasible among U.S. MSM with fluctuating viral load. This complementary approach to clinical care could improve viral suppression maintenance.
需要新的病毒载量监测策略来帮助个体维持不可检测的病毒载量（UVL）。2018 年，美国接受过检测有 HIV 病毒载量可检测的过去史的男男性行为者（MSM）在基线和 3 个月随访时收到了一份干血斑（DBS）检测包，并将标本送回研究实验室。在 56 名同意参与的参与者中，91%的人在基线时和 77%的人在 3 个月随访时返回了标本；74%返回两份标本的人在两个时间点均有 UVL。在家中采集 DBS 和纵向 VL 监测在病毒载量波动的美国 MSM 中是可行的。这种对临床护理的补充方法可以提高病毒抑制的维持率。
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