Infectious Disease Unit, CHU Clermont-Ferrand, COREVIH Auvergne Loire, Clermont-Ferrand, France.
Société Française de Lutte Contre le SIDA, Paris, France.
Pharmacol Res Perspect. 2020 Oct;8(5):e00629. doi: 10.1002/prp2.629.
In France, antiretroviral (ARV) treatment can be dispensed by hospital and/or community pharmacies. Since January 2016, an online patient medication file can be used to optimize dispensing, but medication interviews have not yet been incorporated into this system. To understand both people living with HIV (PLHIV) and their pharmacists' habits and expectations of patient medication file and interviews, two consecutive national surveys were organized. The first one, carried out in October 2016 in care centers, was an anonymous questionnaire for PLHIV. The second one was an online survey for community and hospital pharmacies conducted in February 2017. A total of 1137 PLHIV (68% men, of mean age 50.2 ± 11.5 years, CD4 count 671 ± 354, 90% with undetectable HIV viral load (VL) and 64.2% reporting comorbidities) and 246 pharmacies responded. While the existence of the online medication file is known by 58% of PLHIV, only 40% of pharmacists declare it to be systematically offered. It was offered to 120/694 (17%) PLHIV and 96 (80%) accepted it. Currently, 78 (7%) PLHIV feel well taken care of because they are offered medication interviews, 343/1078 (32%) would like to take advantage of this program, mainly those with a shorter ARV duration (OR ARV duration 0.97 [0.95-0.99]), a VL less often undetectable (OR undetectable VL 0.55 [0.31-0.98]), and those who feel anxious more often (OR anxious 2.38 [1.48-3.84]). These results suggest that better implementation of medication files and interviews will strengthen current clinical pathways.
在法国，抗逆转录病毒（ARV）治疗可以在医院和/或社区药房配药。自 2016 年 1 月以来，人们可以使用在线患者用药档案来优化配药，但药物咨询尚未纳入该系统。为了了解艾滋病毒感染者（PLHIV）及其药剂师对患者用药档案和咨询的习惯和期望，我们组织了两次连续的全国性调查。第一次是在 2016 年 10 月在护理中心进行的，是一项针对 PLHIV 的匿名问卷调查。第二次是 2017 年 2 月对社区和医院药房进行的在线调查。共有 1137 名 PLHIV（68%为男性，平均年龄 50.2±11.5 岁，CD4 计数 671±354，90%的 HIV 病毒载量（VL）不可检测，64.2%的人报告有合并症）和 246 家药房做出了回应。虽然 58%的 PLHIV 知道在线用药档案的存在，但只有 40%的药剂师表示会系统地提供该档案。有 120/694（17%）名 PLHIV 获得了该档案，其中 96 人（80%）接受了该档案。目前，有 78 名（7%）PLHIV 因接受药物咨询而得到了良好的照顾，343/1078（32%）人希望利用这一方案，主要是那些接受 ARV 治疗时间较短的人（OR ARV 治疗时间 0.97[0.95-0.99]）、VL 检测频率较低的人（OR 不可检测 VL 0.55[0.31-0.98]）和经常感到焦虑的人（OR 焦虑 2.38[1.48-3.84]）。这些结果表明，更好地实施用药档案和咨询将加强当前的临床路径。
