Department of Vascular Surgery, Faculty of Medicine, School of Health Sciences, Larissa University Hospital, University of Thessaly, Larissa, Greece -
Department of Neurosurgery, Faculty of Medicine, School of Health Sciences, Larissa University Hospital, University of Thessaly, Larissa, Greece.
J Cardiovasc Surg (Torino). 2021 Feb;62(1):79-86. doi: 10.23736/S0021-9509.20.11427-7. Epub 2020 Sep 10.
The widespread use of endovascular repair in thoracic aorta (TEVAR) pathologies has ameliorated postoperative outcomes. This meta-analysis was designed to investigate the intra-operative use of transesophageal echocardiography (TEE) compared to angiography in patients undergoing TEVAR.
The meta-analysis was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis statement (PRISMA) guidelines. A data search of the English literature was conducted, using PubMed, EMBASE and CENTRAL databases, until November 30, 2019. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach was used to evaluate the quality of evidence and the summary of findings for each of the included outcomes.
The final analysis included 7 articles (183 patients). All patients underwent TEVAR using intra-operative TEE and angiography. The sensitivity and specificity rates of entry points were 0.624 (95% CI: 0.145-0.97) and 0.377 (95% CI: 0.029-0.856), respectively. Regarding the detection of adequate guidewire advancement, the sensitivity was 0.778 (95% CI: 0.288-939) and specifity 0.346 (95% CI: 0.019-0.844). TEE could detect endograft incomplete deployment within acceptable rates of sensitivity and specifity, estimated at 0.616 (95% CI: 0.141-0.971) and 0.365 (95% CI: 0.028-0.845), respectively. The intra-operative detection of endoleaks presented a sensitivity estimated at 0.875 (0.51-0.998) and specificity at 0.698 (95% CI: 0.284-0.904).
Despite the limitations of this analysis, TEE may be evaluated in the current endovascular era, as a useful tool, providing adequate information, on graft deployment and early endoleaks.
血管内修复在胸主动脉(TEVAR)病变中的广泛应用改善了术后结果。本荟萃分析旨在研究在接受 TEVAR 的患者中,与血管造影相比,术中使用经食管超声心动图(TEE)的效果。
该荟萃分析按照系统评价和荟萃分析报告的首选条目(PRISMA)指南进行。使用 PubMed、EMBASE 和 CENTRAL 数据库对英文文献进行了数据检索,检索时间截至 2019 年 11 月 30 日。使用推荐评估、制定与评价(GRADE)方法评估了每个纳入结局的证据质量和研究结果总结。
最终分析纳入了 7 篇文章(183 例患者)。所有患者均接受了术中 TEE 和血管造影引导的 TEVAR。入口点的灵敏度和特异度分别为 0.624(95%CI:0.145-0.97)和 0.377(95%CI:0.029-0.856)。至于导丝推进的充分性检测,灵敏度为 0.778(95%CI:0.288-939),特异度为 0.346(95%CI:0.019-0.844)。TEE 能够以可接受的灵敏度和特异度检测到移植物不完全放置,估计值分别为 0.616(95%CI:0.141-0.971)和 0.365(95%CI:0.028-0.845)。术中检测内漏的灵敏度估计为 0.875(0.51-0.998),特异性为 0.698(95%CI:0.284-0.904)。
尽管本分析存在局限性,但 TEE 可能在当前的血管内时代被评估为一种有用的工具,提供有关移植物放置和早期内漏的充分信息。